This is according to the research of Dr. Lorin Zitwegel from the French National Institute for Medical Research * Next month the International Conference on Personalized Medicine will be held in Herzliya
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The patient's immune system affects the success of chemotherapy treatment on several levels. On the one hand, chemotherapy can kill cancer cells by causing them to mount an immune response, or alternatively, by increasing their susceptibility to immune attack. This is according to a study published in the journal Nature led by Dr Lauren Zitwegel (Zitvogel) together with her colleagues at the Oliver Kepp Institute and Guido Kramer.
Dr. Laurent Zitwegel is the director of research at the National Institute of Medical Research de la Santa in Villejuif near Paris. She mainly specializes inDendritic cells and in the biology of innate factors, in particular with regard to the spread of cancerous tumors, in particular in their effect on the ability to develop a vaccine against these tumors.
In addition, chemotherapy can stimulate factors in the immune system against cancer either directly or by subverting immune suppression mechanisms. Beyond the factors in the cell responsible for its response to toxins (cytotoxic or cytostatic response) as well as the genetic potential of the cancer cells, the state of the immune system activity is a good predictor of the fate of cancer patients who have received conventional chemotherapy or targeted chemotherapy.
After conducting a series of experiments, the researchers hypothesize that relevant immune biomarkers may guide the ability of doctors to perform personalized therapeutic interventions in them, including compensatory measures to help restore or improve the body's immune response against cancer.
On June 29-30, the international conference for the second time will be held in HerzliyaPersonalized medicine PMWC
Abstract of the article in Nature
The cellular response to the vaccine from the journal Cancer Resaerch
One response
I didn't understand the connection to personalized medicine? Also, there was room to pay more attention to the quality of the translation.