immune system

The Hebrew University in Jerusalem. Illustration: depositphotos.com

Two researchers at the Hebrew University will receive grants of 2 million euros each from the ERC

In addition, two outstanding researchers from the Hebrew University of Jerusalem were chosen to join the EMBO young researchers program
Antibiotic resistant bacteria. Illustration: depositphotos.com

An innovative approach to dealing with antibiotic-resistant bacteria

Section of breast tissue from a triple negative breast cancer (TNBC) patient, on the right, and healthy breast tissue, on the left. In the cancer patient, the cancer cells (indicated in light blue) surround cells in their microenvironment that express a high level of CD84 (indicated in purple)

burn the bridges of cancer

The institute's scientists revealed how aggressive breast cancer disrupts the immune response against it, and developed a treatment using an antibody that may be suitable for many types of cancer
Prof. Carmit Levy and Prof. Yaron Carmi

Researchers from Tel Aviv University have discovered a new cancer mechanism, the activation of which eliminates cancerous tumors

Prof. Carmit Levy: Immunotherapy has revolutionized cancer treatment," explains Prof. Carmi, "but about 50% of patients do not respond to the standard treatment - the PD-L1 protein. We found a new protein Ly6a against which treatment with an antibody
A sample from a tumor of a human patient with the most common lung cancer (adenocarcinoma). The presence of senescent cells expressing the proteins P16 (in red) and PD-L1 (in green) can be detected. The cell nuclei in the sample are marked in blue

to open blockages in the immune system

immunotherapy. Illustration: depositphotos.com

Faster, stronger

Weizmann Institute scientists have developed a new approach to increase the rate of division of immune cells in the laboratory, while preserving their ability to kill cancer cells, and have identified optimal time windows in which the cells are particularly lethal. The method may promote
Heart Attack. Illustration: depositphotos.com

Discovery of violations

Copaxone may protect heart muscle cells and improve its function after a heart attack
Imaging of human small intestine tissue using a fluorescence staining method that allows marking a large number of proteins at the same time and thus mapping which proteins are produced in the entire basal area of ​​the intestine

navigate the digestive tract

Photomicrograph of a biopsy from a patient's lungs. Illustration: depositphotos.com

Towards a new generation of treatments for old age diseases

The bacterium Pseudomonas Aeruginosa causes sinusitis A Hrefhttps Depositphotoscom illustration Depositphotoscom A

Fighting antibiotic resistance using peptide mixtures

New research highlights the potential of random mixtures of antimicrobial peptides to significantly reduce the risk of resistance development compared to single peptides. These findings highlight the need for innovative solutions to overcome
In the photo, from right to left: Dr. Tanya Dubovic, Prof. Shai Shen-Or, Dr. Alina Strusvetsky and Dr. Martin Lukachishin

Research sheds light on the constant evolution of the immune system

The researchers of the Rappaport Faculty of Medicine at the Technion show in their article in Nature how the immune system has developed a "developmental space" that allows it to quickly adapt to changes in the environment
The cover photo on the issue: Cell Host & Microbe This is how the bacteriophages (in purple) affect the function of the bacteria by reversing the DNA - a reversal that changes their effect on the immune system. This effect is demonstrated by changing the color of the bacteria from yellow to green. Illustration credit: Tomm Blum

Gut bacteria are able to change their 'software' in response to inflammation, which may affect the immune system

The intestine is a very dynamic organ that is constantly changing structurally, mechanically and chemically, and the intestinal bacteria are required to cope with this dynamism. One of the qualities that may help them in this is plasticity - the ability
Dr. Catherine Vandorna. Photo: Nitzan Zohar, Technion spokesperson

This is how the bone marrow reacts to injuries and infections

Dr. Kathryn Vandorna from the Faculty of Biomedical Engineering at the Technion has developed a new method that allows the monitoring of the formation of immune blood cells in the bone marrow. For this purpose, she used tiny magnetic particles of iron oxide, which
What is needed to prolong life. Illustration: depositphotos.com

A new competition to stop aging with prizes of 101 million dollars

A new competition to stop aging with prizes of 101 million dollars
Bacterial cells before phage infection (left) and after (right). The virus replicates itself inside them and leads to the explosion of the cells and the spilling of their contents (in red - the bacterial DNA spilled from the cell)

Survive with 0% battery: an immune system that drains the cell of energy has been discovered

The new system was discovered in bacteria - but is also used in corals, bees and others
Personalized Medicine Illustrated: depositphotos.com

The discovery that will advance personalized medicine for infectious diseases

This is the first time that researchers succeed in developing personalized tools for infectious diseases, which until now have only been developed for specific diseases such as cancer and Alzheimer's
Microglial cells (in green) in the hippocampus region of the brain of an adult mouse, forming contact points with a new neuron (in red)

The biology of depression

Degeneration of the cells of the immune system in the brain may be the biological cause of depression, and there may be substances that can restore these cells - and be antidepressants
Prof. Michal Schwartz. Photo: Weizmann Institute Spokesperson

Prof. Michal Schwartz from the Weizmann Institute won the Israel Prize for research on the relationship between the immune system and the nervous system

Prof. Schwartz challenged the convention that nerve cells do not regenerate or recover, and discovered that the immune system also takes care of them. She also studied the blood-brain barrier and discovered that it is prevented
Right: Immune clusters in the liver of a mouse containing ILCs, and within them cancer cells (in red). On the left: immune clusters in the liver of a mouse from which ILCs have been removed, and within them cancer cells. The cancer cells thrive more in the mouse liver which contains ILCs

The immune system gets tired - and the cancer spreads

Pools of immune system cells taken from patients and mice with liver cancer and melanoma, partly composed of tired immune cells
Microglial cells that were "ripened" in the laboratory from stem cells derived from ALS patients (in green), the cell nuclei - in blue. Photographed using a confocal microscope

The good mutation

Weizmann Institute of Science scientists have discovered a new pathway that may protect nerve cells in the brain and slow down the development of degenerative brain disease
A mouse intestinal mucosa lined with finger-like protrusions (in white) and containing lymphoid organs (in red) that contain germinal centers (in green). Photographed by confocal microscopy

There is no doubling of promotions: the immune system must choose - short term or long term

When the body's defense systems sacrifice the long term for short term victories
A "topographic map" of a segment on the surface of a T cell. The red areas are the flexible fingers described in the paper (the warmer the color, the higher the labeled area). CCR7 receptors (in black) are located at the highest points on the surface of the fingers

Know when to stop

How do the cells of the immune system know how to brake quickly?
Bacteriophages attack bacteria. Illustration: depositphotos.com

The common fight of bacteria and plants against viruses

A defense mechanism discovered in bacteria may make it possible to improve the resistance of agricultural crops to pests
Plasma cells - B cells of the immune system attack viruses. Illustration: depositphotos.com

The aging immune system: can the wheel be turned back?

Researchers at the Rappaport Faculty of Medicine at the Technion deciphered new aspects of the aging of the immune system - and discovered that it is possible to restore its youth
The triple strategy of the corona: 1. A general decrease in the translation products in the cell; 2. Breakdown of messenger RNA molecules of the cell; 3. Preventing the exit of messenger RNA molecules from the nucleus

The triple of the corona

The scientists of the Weizmann Institute of Science, in partnership with the scientists of the Biological Institute in Nes Ziona, revealed how a unique combination of three mechanisms allows the corona virus to escape the immune system
A diagram depicting the activity of B cells of the immune system. . Photo: depositphotos.com

TA researchers have identified a special group of cells in the immune system shared by malaria, AIDS and lupus patients

In a healthy person, these cells do not exist at all. In patients with malaria, AIDS and lupus, they make up 15%-25% of the B cells
Bacteriophage - a virus that attacks bacteria. Illustration: Illustration: depositphotos.com

A mysterious component in bacteria has been discovered as a last line of defense against viral infection

Besides solving a 36-year-old mystery, Weizmann Institute of Science scientists have identified thousands of types of these components, which may be used in gene editing
immune system. Illustration: shutterstock

Immune memory cells are stable over time after recovery from corona

This is according to a joint study by Tel Aviv University and Hasharon Hospital (Rabin Medical Center). The researchers estimate that in the event of repeated exposure to Corona, those who recover from the disease may be protected from a second illness -
The immune system attacks invading viruses. Illustration: shutterstock

Fighting fiercely against tiny enemies - the story of the immune system

Did you know that our immune system consists of two subsystems? One is born, and the other is acquired during our lives. Both together fight invaders (bacteria, viruses, etc.) as much as they can. So why do we need vaccines? Because two too
A virus attacks and the immune system defends. Illustration: shutterstock

Researchers offer a new approach to dealing with the corona virus: putting the immune system into action even before the body is attacked

The researchers actually suggest increasing the power of the innate immune system - the first line in the fight against the virus, before the acquired immune system (specific to a particular pathogen) comes into action.
survival of the fittest. Illustration: shutterstock

What does "survival of the fittest" mean? in the corona epidemic

The coronavirus affects older people at greater rates. Illustration: Image by Tumisu from Pixabay

The elderly are especially at risk because of the way the immune system ages

Measles symptoms. Illustration: shutterstock

Measles erases immune memory of other diseases

The researchers mapped the different versions of circular nucleotide systems

Which is good for bacteria

Illustration of a primary Cornell spot (left) attached to an antibody fragment (center) while binding to the HER2 cancer cell receptor (right). The dot and the antibody attached to it together are less than 8 nanometers in diameter, the size threshold for removal from the body by the kidneys.

An effective weapon to fight cancer - antibodies

eosinophils. Photo: Prof. Ariel Munitz, Tel Aviv University

A new method for treating colon cancer by strengthening the immune system

Nobel Prize for Medicine 2018: Harnessing the immune system to fight cancer

Looking at: mapping the intercellular communication, carried out by cytokines, between the cells of the immune system. Illustration: The Technion

The immune system: opening the black box

CAR T cells attack a cancer cell. Source: Rita Elena Serda, Duncan Comprehensive Cancer Center at Baylor College of Medicine, National Cancer Institute, National Institutes of Health.

The army to destroy cancer