Personalized medicine

Using fMRI. Illustration: depositphotos.com

Breakthrough: fMRI brain training increased antibodies after hepatitis B vaccination

A study by Tel Aviv University, the Technion, and Ichilov in Nature Medicine found that positive anticipation that activates the VTA region of the reward system is associated with a stronger immune response in humans.
Lung on a chip. Illustration: depositphotos.com

“Breathing lung on a chip” from single human cells reveals early stages of tuberculosis

A new model in Science Advances combines lung cells, blood vessels, and immune cells from the same genetic origin, simulates breathing, and shows how early foci of cellular damage are formed during infection with the tuberculosis bacterium.
Prostate cancer. Illustration: depositphotos.com

Making drug resistance a weak point in metastatic prostate cancer

A new computational tool, SpotNeoMet, developed at the Weizmann Institute, detects resistance mutations that recur in many patients and create neoantigens – a possible target for “precision” immunotherapy for broad patient groups
The mechanism that allows breast cancer to metastasize to the brain has been deciphered. Courtesy of the researchers

For the first time, a mechanism that allows breast cancer to metastasize to the brain has been deciphered

Researchers from Tel Aviv University have identified a link between loss of p53 activity (and sometimes deletions in the short arm of chromosome 17) and the adaptation of breast cancer cells to the brain environment through fatty acid pathways and communication with
Tel Aviv University's IGEM 2025 team. Photo by Tel Aviv University Spokesperson

Tel Aviv University's IGEM team leads breakthrough in synthetic biology against lung cancer and promotes national high school competition

Along with developing models and software that could transform the study of lung cancer and genetic diseases, Tel Aviv University's IGEM team collaborated with the ORT Network and organized a synthetic biology competition for high school students with the participation of
Computer simulation showing the gradual passage (from left to right) of the protein alpha-lactalbumin through a solid-state nanopore with a diameter of approximately 4 nanometers. The passage of the protein through the pores allows the reading of the sequence of markers attached to the cysteine ​​groups (red color) and the identification of the protein.

Without antibodies and without amplification: Rapid identification of intact proteins with technology developed at the Technion

Nano-needle technology from Prof. Amit Meller's lab enables rapid, digital identification of individual proteins in near real-time, paving the way for early diagnosis of cancer and other diseases through simple blood tests.
Five-day-old zebrafish embryos under a microscope: the normal embryo (top) and the transgenic embryo (bottom) carrying the gene with the disease-causing mutation. It can be seen that in the transgenic embryo the main lymphatic vessel is abnormally enlarged

From the clinic to the aquarium: New zebrafish-based drugs for a rare lymphatic disease

A unique collaboration between the Weizmann Institute of Science and Sheba Medical Center led to the discovery of two potential drugs for a life-threatening disease of the lymphatic system.
From right: Dr. Naama Darzi, Prof. Ayelet Erez, Dr. Natalie Rosenfeld and Dr. Elizaveta Bab-Dinitz. Photo by Weizmann Institute Spokesperson

It's all in the head: Blocking the communication channel between the brain and liver may prevent life-threatening weight loss in cancer patients

Research at the Weizmann Institute of Science demonstrates how communication between the brain and the body's organs plays a critical role in health and disease
Microscopic image of a fetal kidney grown in the laboratory. Photo: Sheba Spokesperson

For the first time in the world: Sheba and Tel Aviv University researchers grew fetal kidney components from stem cells

The kidney grew and developed over many months and underwent processes similar to those in pregnancy | The organoid allows for the development of regenerative medicine treatments, testing drug toxicity during pregnancy on fetal kidneys, and shedding light on birth defects
Bandages may now be smart. Illustration: depositphotos.com

New bioactive dressing promises faster healing for diabetic wounds

Researchers have developed an innovative bandage that combines biologically active substances, which helps accelerate wound closure and prevent infections – with the potential to significantly improve the quality of life of those with diabetes.
The system was developed by the research group led by Prof. Hosem Haik. Credit: Xia Gong

New wearable system for real-time diabetes monitoring

Joint development by Prof. Hussam Hayek from the Technion and researchers from Sun Yat-sen University enables glucose measurement and personalized metformin dosing using microneedles and nanobiological sensors
AI double will test personalized medicines. Illustration: depositphotos.com

A personal AI double will predict diseases – and help prevent them

Based on the advanced database of the Human Phenotype Project and artificial intelligence models, Weizmann Institute of Science scientists created a "digital twin" that will help predict the medical future of each participant.
Prof. Moran Berkowitz and Prof. Naama Geva Zatorsky, winners of the ERC Poc grant for 2025. Photo: Technion Spokesperson and Lucido Studio.

Technion researchers win EU "feasibility grants" for developing breakthrough technologies in medicine and optics

Prof. Moran Berkowitz from the Faculty of Mechanical Engineering and Prof. Naama Geva-Zatorsky from the Faculty of Medicine will develop technologies for the production of customized lenses and personalized melanoma treatment – thanks to ERC Proof of Concept grants
Artificial intelligence in medicine. Illustration: depositphotos.com

Microsoft's artificial intelligence is leaving doctors behind

A new study shows a digital doctor panel leading to an accuracy of about 80% in complex medical diagnoses – far beyond the average of general practitioners. This is a breakthrough that could change the future of medicine, and perhaps even
The deadly plague of the "Black Death" in Naples, 1656. Engraving by Miko Spadaro, an eyewitness to the plague. Illustration: depositphotos.com

Israeli researchers have developed a 100% effective mRNA vaccine against antibiotic-resistant bacteria

Researchers from Tel Aviv University and the Institute for Biological Research have developed an innovative vaccine against one of the deadliest bacteria in history – Yersinia pestis, which caused the Black Death in the Middle Ages.
Research team: Back row (right to left): Prof. Moran Rubinstein, Prof. Keren Avraham and Prof. Aviva Petal-Wolevsky. Front row (right to left): Daniel Gelber, Mor Yam, Shir Quinn. Photo: Tel Aviv University

Israeli researchers on the way to a cure for one of the world's rarest diseases

Following a request from the family of Adam, an 8-year-old boy suffering from an extremely rare genetic disease, researchers from Tel Aviv University developed a revolutionary mouse model that helps understand the disease and test effective treatments.
Moving on. You can now select a variety of features in advance. Illustration: depositphotos.com

New app lets parents choose their embryos

Nuclear Genomics Company Offers New Digital Interface for Parents in IVF Process, Allows Screening of Embryos Based on Genetic Characteristics and Medical Risks – But Raises Deep Ethical, Medical, and Social Questions
Leukemia. Illustration: depositphotos.com

The blood test that will identify the risk of leukemia – and may replace bone marrow aspiration

Just days after their laboratories were damaged in an Iranian attack, Prof. Liran Shlush and Prof. Amos Tanai publish groundbreaking findings that are expected to advance the field of blood cell medicine.
The rise of the clones. Illustrator: Itay Chen (student at the Rappaport Faculty of Medicine and professional illustrator of scientific illustrations).

Technion discovery: Genetic "fingerprint" may improve the personalization of immunotherapy treatments

Researchers at the Rappaport Faculty of Medicine have identified a genetic "fingerprint" that helps predict the effectiveness of these treatments.
Two human heart models, one simulating a healthy heart and the other a diseased one. Photo: Dassault Systèmes

Members of the "Living Heart" project are testing a new generation of a customizable model

Dassault Systèmes enters the next phase of the "Living Heart" project with AI-based virtual twinning * Matching and automation of virtual models of the heart, based on AI, will help simplify and accelerate
Microscopic image of adipose tissue and identification of unique fat cells. Credit: Prof. Assaf Rodich

New types of fat cells discovered in the human body: a breakthrough in personalized medicine

Leading international research from Ben-Gurion University discovers unique subpopulations of fat cells and provides innovative treatment approaches to prevent obesity complications
Illustrative epigenetics: depositphotos.com

The Technion will award the Harvey Prize to three groundbreaking researchers in the field of cancer epigenetics

Prof. Peter Jones, Prof. Steven Bailin and Prof. Andrew Feinberg will receive the Harvey Award in the field of science and technology for their contribution to the diagnosis of diseases and the development of treatments based on the understanding of epigenetic mechanisms
Improving a disease prediction model. The image was prepared using DALEE and is not a scientific image.

A new model can change the ways of decision-making in healthcare systems

Researchers from the Hebrew University improved Elixhauser's comorbidity model and improved the accuracy of predictions about the duration of hospitalization, risk of mortality, re-hospitalization and increased treatment
Glucose measuring device on hand, connected to diabetes management with advanced technology that predicts sugar levels four years ahead. ISHA SALIAN

Weizmann Institute researchers, Pheno.AI and NVIDIA developed a creative artificial intelligence model to predict blood sugar levels up to 4 years ahead

The researchers of the three organizations reveal GluFormer, a generative artificial intelligence model (Generative AI) based on a transformer architecture similar to GPT from OpenAI - but instead of text - it produces a prediction of levels
cancer cell Illustration: depositphotos.com

What predicts your cancer type?

From the right: Dr. Shagit Meir, Dr. Eva Heinig, Dr. Nikolai Kuzmich, Prof. Assaf Aharoni, Dr. Shirley Berman, Dr. Yoav Peleg, Hila Hart and Dr. Ilana Rogchev (photographed in the nursery Regev)

Hallucinations of cacti

The secrets of the production of mescaline have been revealed - a natural hallucinogenic drug with therapeutic potential * The drug extracted from the extinct peyote cactus has been used in religious ceremonies for thousands of years. Its effect on serotonin receptors in the brain
Imaging of human small intestine tissue using a fluorescence staining method that allows marking a large number of proteins at the same time and thus mapping which proteins are produced in the entire basal area of ​​the intestine

navigate the digestive tract

In the top row: connectivity in healthy brains, in the bottom row: connectivity in the brains of head-injured people. In the right column: connectivity in the brains of girls and women before menstruation, in the left column: connectivity in the brains of girls and women after menstruation.

Personalized medicine - and gender

Evidence is growing that brain damage in girls, which occurs during puberty, impairs cognitive function and the strength of the brain network
Right: Prof. Ronit Sachi-Painero and doctoral student Shani Koshrovsky-Michael

Innovative technology: Two drugs are launched together, attacking cancerous tumors simultaneously

Innovative technology will allow two drugs to be launched to simultaneously attack a cancerous tumor
Personalized medicine. The image was prepared with the help of DALEE artificial intelligence software and is not a scientific image

Towards a treatment for Huntington's: two small molecules may revolutionize the treatment of an incurable disease

Weizmann Institute scientists have shown in a mouse model that the drugs succeed in penetrating through the blood-brain barrier, delaying the progression of the disease and even reversing it
Emma Twain is a virtual character who participates in medical experiments. Photo by Dassault Systèmes

Emma Twine, a Dassault Systèmes virtual character, demonstrates how virtual twins advance medical development

Emma Twin will share through social media posts how she, as a virtual twin, helps doctors and researchers better understand diseases and the effectiveness of treatments - without endangering flesh and blood patients
Personalized Medicine Illustrated: depositphotos.com

The discovery that will advance personalized medicine for infectious diseases

This is the first time that researchers succeed in developing personalized tools for infectious diseases, which until now have only been developed for specific diseases such as cancer and Alzheimer's
Photo: depositphotos.com

Artificial intelligence in the service of cancer medicine

A technology based on artificial intelligence may quickly and simply decode genetic and molecular information about cancer tumors. On the horizon: personalized medicine for cancer patients
Prof. Dan Farr (Photo: Yonatan Blum)

Unique RNA technology for personalized cancer medicine

The nanomedicine that attacks cancer twice: both improves the effectiveness of chemotherapy and strengthens the immune system
A deaf person undergoes a hearing test. Illustration: depositphotos.com

Researchers from Tel Aviv University have developed genetic therapy for deafness

A new study from Tel Aviv University presents an innovative treatment for deafness, which is based on the introduction of genetic cargo into the cells of the inner ear. As part of the treatment, the genetic load is inserted into the damaged cell in such a way that it actually "repairs"

Confused teacher: 5 things you should know when choosing a comprehensive genomic test for cancer diagnosis

What parameters should be taken into account when choosing a genomic test for cancer?
Who is a comprehensive cancer genomic test not suitable for?

Comprehensive genomic testing in cancer: for whom is the test not suitable?

Comprehensive genomic testing in cancer: great hope, but not for everyone
Disease at first glance: when a cell of the immune system (macrophage, in blue) meets a bacterium (in red), what happens in the first 48-24 hours is crucial

An algorithm that may predict the chance of contracting tuberculosis

Cellular "selfie": an mTEC cell that was photographed using the new method called PLIC. The green dots indicate an interaction between proteins that helps prevent an autoimmune attack. Source: Weizmann Institute magazine.

Security selfie