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Cancer research

In the future, will lung cancer patients be able to receive chemotherapy using an inhaler at home? Source: illustration - Nic McPhee.

Inhaled chemotherapy for lung cancer

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Cancer metastasis in the brain, originating from lung cancer. Photo: Marvin 101, Wikimedia.

Two genes responsible for the development of brain metastases among lung cancer patients have been identified

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Illustration: The Trojan horse represents the virus, which enters the cell and causes the creation of proteins. Their purpose is to call the immune system, so that it attacks the cancer cell only, without harming healthy cells. Source: Courtesy of the Hebrew University.

Researchers have developed a "switch" that activates the immune system to attack cancer cells when it detects signs of the disease

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Hepatocellular carcinoma liver cancer. Source: Ed Uthman.

New liver cancer research reveals potential targets for treatment

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The attached images show how E260 dramatically affects the mitochondria of metastatic cells. From the study.

Researchers have developed a substance that kills cancer metastases without harming normal cells

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Bacteria (in green) inside pancreatic cancer cells (AsPC-1 cells). The nuclei of the cells are colored in blue and the intracellular fluid in orange. Source: Weizmann Institute magazine.

Fifth brother-in-law: bacteria that live inside cancerous tumors disrupt the drug treatment

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CAR T cells attack a cancer cell. Source: Rita Elena Serda, Duncan Comprehensive Cancer Center at Baylor College of Medicine, National Cancer Institute, National Institutes of Health.

The army to destroy cancer

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Fluorescent actin fibers. Produce rounded folds on the cell membrane. Source: Weizmann Institute magazine.

Reshaping the surface: wave fronts create folds in the cell membrane

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Embryonic stem cell colonies as seen under a microscope: the cells differentiated in an orderly manner when their genome contained a normal copy of the p53 gene (left), but not when p53 was missing (right). Source: Weizmann Institute magazine.

The new role of the guardian of the genome

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Cancerous breast cells (in blue). Source: NIH.

Researchers were able to reduce the risk factors for the spread of cancer metastases after resection of the primary tumor

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leukemic cells. Evolve from "cancer stem cells". Photo: Mary Ann Thompson / Wikimedia.

Is it possible to identify, already in the initial diagnosis, signs that the cancer is going to return?

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Prototype of the Watson system, 2011. Photo: Clockready / Wikimedia.

Watson set a record in analyzing the genetic makeup of cancer patients

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The area of ​​operation in the peritoneal membrane of a mouse. The red marking shows the expression of LOX; The green marking shows the hypoxia (lack of oxygen) in the cells. Source: Courtesy of the Technion.

Battle of Lima

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waves in the cell membrane. Source: From the study - Fronts and waves of actin polymerization in a bistability-based mechanism of circular dorsal ruffles.

Researchers shed new light on the movement of waves across cell membranes, which may affect cancer research and treatment

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Dr. Ayelet Erez. To turn to side ways. Source: Weizmann Institute magazine.

The connection between a rare childhood disease and the fight against cancer

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Photomicrograph of senescent cells in a mouse - cells that "retire" and stop dividing, but do not die - are always present and even play some important roles in the body, for example in wound healing. But in aging organs, these cells are not eliminated at the proper rate, and can accumulate and damage Source: Y tambe, Wikimedia.

Get rid of old hair

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Schematic diagram of the system and the DNA molecules conjugated to a synthetic molecule that pulls them through the hole. Right: an example of the optical signal (in two colors) indicating the level of methylation. Courtesy of the Technion.

Unimolecular cancer diagnosis

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Diagram from the article, which presents the innovative method developed: "We pack tiny amounts of the anti-cancer drugs inside dedicated nanoparticles that we developed. The uniqueness of these nanometer packages is that they flow in the bloodstream to the tumor and there are swallowed by the cancer cells. To these packages we attach "In advance, artificial DNA sequences are used as barcode readers of the drug's activity in the cancer cells. After 48 hours, a sample (biopsy) is taken from the tumor, and the barcode analysis provides accurate information on the cells that were destroyed (or not) by each drug." Source: Zvi Yaari et al., Theranostic barcoded nanoparticles for personalized cancer medicine, Nature Communications 7, 2016.

Personalized medicine for cancer treatment

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From the right: Prof. Ora Peltiel, director of the School of Public Health at the Hebrew University and senior physician in the hematology department at Hadassah Ein Kerem Hospital and doctoral students Gefen Kleinstern and Rania Abu Sir (who received their PhDs as part of the research). Source: The Hebrew University.

Is there a difference between Jews and Palestinians in the risk factors of getting cancer?

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X-ray of a healthy breast (left) versus a breast with cancer. Source: Wikimedia.

The population of bacteria in the breast affects the risk of developing cancer

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Why don't genetic tests for cancer provide clearer answers?

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Thyroid cancer cells. Source: NASA / Team Daniela Grimm.

Researchers have developed a new approach to the targeted elimination of aggressive cancer cells

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Cross-sectional image from a confocal microscope: breast cancer cells with high metastatic potential push into a polyacrylamide gel with a stiffness of 2.4 kPa, where this section is at a depth of 10.6 microns below the surface of the gel. In the picture you can see the cell nuclei (red), the actin element in the intracellular skeleton (green) and the connections of the cells to the surface at connection centers (blue).

A fatal warning: researchers have developed a method for estimating the metastatic potential of cancerous tumors

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From the study: Fluorescent radiation emission map of cells treated with the organometallic compound. Source: Dr. Carlos Sanchez-Cano et al. Synchrotron X-Ray Fluorescence Nanoprobe Reveals Target Sites for Organo-Osmium Complex in Human Ovarian Cancer Cells, Chemistry - A European Journal, 2017.

An organic-metallic compound for the elimination of cancer cells

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Simulation of the first solar exoplanet discovered around a main sequence star - 51 Pegasi b. Source: ESO/M. Kornmesser/Nick Risinger.

The 2017 Wolf Prize winners in the arts and sciences have been announced

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