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"Tweezers-DNA" Tiny captures and releases objects on demand

Among the uses of the discovered material: microsurgery, the transport of drugs and genes in the field of gene therapy and the production of electrical nanocircuits for futuristic electronic devices.

DNA tweezers from the scientific article
DNA tweezers from the scientific article

Researchers from China report the development of DNA "tweezers". News, the first of its kind, capable of grasping and releasing objects on demand. The microscopic tweezers could have several possible uses, the researchers point out, including - microsurgery, transporting drugs and genes in the field of gene therapy and in the production of electrical nanocircuits for future electronic devices.

Researcher Zhaoxiang Deng and his colleagues point out that other scientists have also developed tweezers composed of DNA. – the double helix compound that is the code of life. These tweezers are able to open and close in response to complementary chemical components found in the DNA backbone. However, building this type of tweezers, which can grasp and release objects just like real tweezers, remains a bioengineering challenge - until now.

The scientists describe the development of a pair of DNA tweezers. consisting of four DNA strands - Three of them are used as "arms". In laboratory experiments the scientists showed that they are able to grasp a piece of DNA. using the arms of the tweezers and releasing it as needed using a controlled series of changes in the hydrogen bonds and the pH level. The scientists used a fluorescent gel to confirm the effectiveness of the tweezers.

The original publication of the study

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  1. Nanotech is an exciting and exciting field and I look forward to continued development and applications in this field which, combined with biotech, can lead to the most significant breakthroughs in science and human health and in our lives more than any other revolution...

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