Comprehensive coverage

ALS

Left: cells with a mutant FUS protein that causes accumulations (in green) and leads to ALS disease. Right: the cells with the protein/chaferon (in pink) that manages to prevent the accumulations

fight degenerative diseases

The proteins and mechanisms required to fight the protein accumulations that lead to neurodegenerative diseases have been identified
Microglial cells that were "ripened" in the laboratory from stem cells derived from ALS patients (in green), the cell nuclei - in blue. Photographed using a confocal microscope

The good mutation

Weizmann Institute of Science scientists have discovered a new pathway that may protect nerve cells in the brain and slow down the development of degenerative brain disease
ALS disease. Image: shutterstock

The toolbox for fighting ALS proteins

  • No comments
Technion researchers have discovered proteins in our bodies that are able to prevent processes that cause neurodegenerative diseases
An eye of a fruit fly engineered to develop an ALS-like disease. Left: Defective protein aggregates leading to ALS-like degeneration. Right: the eye returned to normal following the expression of one of the "sumo" proteins

Heavy weight pellets

Weizmann Institute of Science scientists deciphered the molecular mechanism of "return to normal" and discovered that it is based on labeling proteins for destruction with a special code known as "SUMO"
MRI scan of an ALS patient. Source: Frank Gaillard, Wikimedia.

Searching for the genetic roots of ALS in new territories

  • 3 תגובות
Intestinal bacteria. Photo: Eran Alinev's laboratory, Weizmann Institute

The intestinal bacteria may influence the development processes of ALS disease

  • 3 תגובות
ALS disease. Illustration: shutterstock

For the first time: genetic mapping of all ALS patients in Israel

  • No comments
ALS disease. Illustration: shutterstock

A new artificial intelligence platform for monitoring and predicting the progression of ALS disease

  • No comments
ALS disease. Illustration: shutterstock

Immunity Pharma announces the start of a clinical study in ALS patients with the original drug IPL344

  • No comments
Stephen Hawking at the Science Museum in Jerusalem, December 2006. Photo: Avi Blizovsky

A new discovery paves the way for the development of a treatment for the degenerative disease ALS

  • One response
MRI scan of an ALS patient. Source: Frank Gaillard, Wikimedia.

New drugs for ALS are on their way to clinical trials

  • No comments
Neurons of a mouse embryo grown in a Petri dish. The axons, the extensions of the nerve cells, are the green extensions in the picture. Source: NIH.

A little less, a little more

  • No comments
Treatment of an ALS patient. Source: Pison Technology website, one of the companies that won the award.

Peres Chaim Association awarded a grant of 600 thousand dollars for the development of innovative communication systems for ALS patients

  • No comments
Prof. Stephen Hawking in a plane that allows training in zero gravity conditions. Photo: NASA

A new study sheds light on the important effect that the levels of chaperone proteins have in the muscular dystrophy disease ALS

  • One response

Survival - in the brain

  • No comments

The great atrophy of the brain

  • One response
Very low expression level of MIF in motor neurons Photo: Dr. Adrian Israelson's laboratory team, Ben Gurion University

Researchers have discovered a new component of selective damage in the muscular dystrophy disease ALS

  • 3 תגובות
Bacteria attack nerve cells. Illustration shutterstock

When normal proteins go wrong / Tara Hal

  • No comments
Eddie Redmayne and Felicity Jones play the characters of Stephen and Jane Hawking. In the photo - the scene of the graduation ball of the university in Cambridge in the mid-sixties. Photo: PR

God as a supporting character in the movie "The Theory of Everything" - a kind of biography of Stephen Hawking

  • 55 תגובות
Respirator. Photo: shutterstock

First case of euthanasia in Israel: the Attorney General allowed the judge to allow euthanasia for an ALS patient who requested it

  • 3 תגובות
Prof. Stephen Hawking and the new communication system. Intel PR photo

Intel unveiled the new communication system it developed for Prof. Stephen Hawking

  • One response
Medicines. Illustration: shutterstock

Small molecules, big hopes

  • 2 תגובות
Neurons - XNUMXD illustration: shutterstock

Development at Ben-Gurion University: the possibility of extending cell life and thus slowing down the development of ALS disease

  • One response
Induced embryonic stem cell colony Credit: Haruhisa Inoue's Laboratory, CiRA, Kyoto University)

Induced stem cells (iPS) in the service of scientific research - a potential cure for ALS?

  • One response
Coloring of the meeting areas between nerve cells (green) and muscle (red). The yellow staining represents complete overlap between the nerve cells and the muscle in normal mice (bottom). In transgenic mice, which lack microRNA in nerve cells that innervate muscles, only the muscle staining is visible (above, in red), because the nerve in the junction area is diseased. Illustration: Weizmann Institute

ALS - suddenly in the middle of life

  • One response
The motor neurons, which control voluntary muscle movement, gradually degenerate. As a result, the patient loses the function of most muscles
Science website logo
SEARCH