Comprehensive coverage

Diseases

A cancer cell divides. Illustration: depositphotos.com

"Silent" mutations can predict the development of cancer cells

  • No comments
Researchers from Tel Aviv University have shown that silent mutations, i.e. those that do not change the amino acid sequence of the proteins, are also not innocent
Blood cancer cells compared to normal blood cells. Illustration: depositphotos.com

Another component in the mechanism that causes leukemia was discovered

In a study conducted on blood samples from patients and those recovering from leukemia, unique sequences were found that control genes that contribute to the spread of the disease. "By investigating these genes we can learn how to prevent the disease from progressing and even develop future drugs to prevent it"
Prof. Bat Sheva Kerem, photo: Douglas Guthrie, Hebrew University.

A new drug for the treatment of cystic fibrosis patients

Plasma cells - B cells of the immune system attack viruses. Illustration: depositphotos.com

The aging immune system: can the wheel be turned back?

  • No comments
Researchers at the Rappaport Faculty of Medicine at the Technion deciphered new aspects of the aging of the immune system - and discovered that it is possible to restore its youth
Lead poisoning. Illustration: depositphotos.com

A study of human bones from 10,000 BC to the 17th century found that the concentration of toxic lead in bones varies depending on the rate of mining

Prof. Yigal Aral: "In light of the expected dramatic increase in the production of lead and other toxic metals, we warn of a large-scale health risk, especially in countries where there is no regulation and orderly monitoring of environmental pollution and human poisoning"
Prof. Neta Erez. Photo: Tel Aviv University spokesperson

Changes in the lung tissue indicate preparation for the absorption of breast cancer cells

  • One response
The findings are of great importance because they may allow diagnosis and preventive treatment before the appearance of the fatal metastases
Photomicrograph: the density of green-red-purple colors indicates the existence of hybrid cells at the tendon-muscle interface. In green - the muscle fibers; In red - LOXL3 RNA is expressed in tendon and tendon-muscle junction. LoxL3 is an enzyme found at the ends of the developing muscle fibers and is responsible for building the muscle tendon junction. In purple - MyoD RNA is expressed within the muscle itself. MyoD is a gene responsible for muscle cell differentiation. Photo courtesy of the Technion Spokesperson

How are inter-tissue interfaces formed?

  • No comments
Researchers at the Rappaport Faculty of Medicine at the Technion discovered that the connection between tendons and muscles is formed by hybrid cells that merge with the muscle fibers and "know" how to cause the ends of the muscle to express tendon characteristics
the heart. Illustration: depositphotos.com

From the heart

  • No comments
A section of the digestive system of a Crohn's patient. Illustration: depositphotos.com

The secret is in the texture

Changes in the intercellular texture may predict inflammatory bowel disease
The most common types of brain cancer. Illustration: depositphotos.com

A new immunotherapy helps the cells of the immune system locate the deadly glioblastoma brain cancer cells and eliminate them

  • No comments
The researchers relied on the CAR-T technology, which uses genetic engineering to improve the function of the immune system's T cells in their war on cancer cells. According to the researchers, the method they developed may help patients with various types of brain cancer, as well as solid tumors in other organs
Drug transport into cells. Courtesy of Prof. Dan Farr, Tel Aviv University

Progress in transporting drugs only to cells infected with cancer or viruses without harming healthy ones

  • One response
Prof. Dan Farr, Tel Aviv University: "Our development actually changes the world of antibodies. Today we flood the body with antibodies that are indeed selective, but also damage the healthy cells. We removed non-inflammatory cells from the game, and with a simple injection we succeeded in damaging only the inflammatory cells at that moment Given"
A lung lobe of a mouse with cancer cell metastases expressing phosphorylated protein, to allow quantification and measurement of the metastases. Credit: Dr. Avi Maimon.

Groundbreaking research: a new protein has been found that significantly inhibits cancer metastasis

  • One response
A protective protein, which was generally known to be effective against blood clots, was found to be capable of inhibiting the most violent means of cancer in the human body - metastasis. Prof. Tal Borshtin-Cohen, the leader of the research, believes that the surprising discovery explains why there are quite a few anti-cancer treatments that fail: "The understanding that protein S helps the body fight metastases is a warning light for anti-cancer treatments, which are designed to inhibit this protein's pathway"
A diagram depicting the activity of B cells of the immune system. . Photo: depositphotos.com

TA researchers have identified a special group of cells in the immune system shared by malaria, AIDS and lupus patients

  • No comments
In a healthy person, these cells do not exist at all. In patients with malaria, AIDS and lupus, they make up 15%-25% of the B cells
Prof. Ilana Gozes. Photo: Tel Aviv University spokesperson

A molecule for the treatment of Alzheimer's and impotence was found to be particularly effective in preventing infections in orthopedic implants

  • 2 תגובות
Researchers from Tel Aviv University have developed a product that protects the bone tissue and it will be registered as a new patent * The product is designed to prevent bone loss around orthopedic implants, dental implants and teeth
A XNUMXD scan illustrating the penetration of the blood vessels into the implanted bone within the resulting tissue suspension. Courtesy of Prof. Shulamit Levenberg and Dr. Idan Radansky, Technion

Success in creating an engineered implant that replaces damaged bone tissue

  • 2 תגובות
Measuring heart muscle cell beats for a few minutes (left) does indeed reveal deviations from the ideal beat rhythm - a beat every second - but when this is done over several hours (right) a new pattern is revealed: slower or faster than average beats that appear in clusters of 10 to 30 minutes

The strange dance of the heart

Scientists at the Weizmann Institute and the Technion have discovered clues to the existence of a slow regulatory mechanism in heart muscle cells designed to regulate the rhythm of their beats, and to ensure that it is as close as possible to a cycle of one beat per second
Prof. Ronit Sachi Fainero and Elam Yeni. Photo: Tel Aviv University

Activating the brain's immune system against the deadly glioblastoma cancer makes it possible to stop its spread

  • 2 תגובות
Researchers from Tel Aviv University have identified a failure in the brain's immune system that increases the division and spread of glioblastoma cancer cells instead of inhibiting them. Now they are looking for ways to turn the situation around
Illustration: shutterstock

Not only Corona: Israel's medical problems - in numbers

An alternative report on the state of health of Israelis: Who gets more cancer - men or women? Where are more affected by diabetes - in the north or in the center? What are the most common surgeries?
The location of the appendix in the digestive system. Image: depositphotos.com

Things Yoram knows: the worm-shaped appendix

  • 2 תגובות
This week we were informed of the return of the Prime Minister's wife, Sara Netanyahu to her family after surgery to remove the appendix. Along with the sigh of relief, interest arises in Neta's question: why do you need the appendix if you take it out and you can live without it?
Insulin and human cell. Image: depositphotos.com

New data on corona patients with diabetes: 20% die within 28 days of entering the hospital

  • No comments
In May 2020 preliminary results from CORONADO with a smaller sample showed that 10% of patients with diabetes and corona died within 7 days of hospital admission.
wisdom teeth. Image: depositphotos.com

Things Yoram knows: Who needs wisdom teeth?

  • 2 תגובות
His mouth is lethargic and the hum of the drill still echoes in his ears. He turns to C with a desperate question: Who needs wisdom teeth?
Prof. Yaakov Nachmias. Photo: Hebrew University Spokesperson

Rapid development of medicines with the help of bionic chips, without the need for animal experiments

Targeted elimination of a cancer cell. Photo: depositphotos.com

Researchers at the Technion have developed a new approach for the selective elimination of cancer cells

  • No comments
The research group of Prof. Tomer Shlomi from the Faculty of Computer Science, the Faculty of Biology and the Lockey Center for Life Sciences and Engineering at the Technion discovered a process based on which it is possible to selectively and specifically damage cancer cells without causing damage to healthy tissue
The consequences of damage to the control mechanism for the separation of chromosomes (SAC) and the KIF18A enzyme in normal cells compared to aneuploid cells

New research reveals a weak point in cancer cells

  • No comments
Researchers from Tel Aviv University shed light on a 140-year-old mystery in an article published in Nature. The research shows for the first time how an abnormal number of chromosomes (aneploidy) - a unique feature of cancer cells that has been known to researchers for decades - can become a weak point of these cells. The research may in the future lead to the development of drugs that will take advantage of this weak point for targeted damage to cancer cells
Medical imaging. Photo: depositphotos.com

Development of a radioactive marker to identify small and aggressive cancerous tumors

  • No comments
A marker developed in a new Israeli study by the University of Bar-in and applied by the start-up company Isotopia will not only determine if it is a malignant or benign tumor but also determine how aggressive it is, and all this will be done in one image and avoid a biopsy
Science website logo
SEARCH