Diseases

Cosmic scene with DNA, stars, solvents and atomic circles in oral flow.

Kidney test

red blood cells Illustration: depositphotos.com

The fight for iron: How disease-causing fungi exploit our blood – and what might stop them

Ultra-processed food. Illustration: depositphotos.com

Like cigarettes, only on a plate: Why ultra-processed food is a national health challenge

Dr. Tair Ben-Porat and Prof. Shira Zalbar-Sagi from the University of Haifa explain why the US debate on restricting the purchase of sugary drinks with food stamps reinforces a shift from personal to state responsibility—and what Israel can learn
HIV virus. Illustration: depositphotos.com

The microbiome as a hidden protector: Gut bacteria partially compensate for HIV damage to the intestinal mucosa

A new study conducted in Israel and Ethiopia, led by researchers from the Weizmann Institute and Hadassah, reveals that the microbiome partially compensates for the damage that HIV causes to immune system cells in the intestinal mucosa and may lead to treatment directions.
Genetic testing for BRCA1 and BRCA2. Illustration: depositphotos.com

BRCA genes not only protect against cancer but also regulate DNA repair pathways in a complex manner

BRCA1 and BRCA2 are not “cancer genes,” but the guardians of the genome: New study maps checkpoints in DNA repair that may explain differences in risk and response to treatment
The innovative concept in the image chosen for the cover of the Science Translational Medicine issue. Credit: Dr. Shadi Farah; Adaptation: Maya Levy and Edouard Odeh

Biological implant with crystalline protection: Technion researchers have developed an “artificial pancreas” that may eliminate the need for insulin injections in type 1 diabetes

Researchers at the Technion have developed a biological implant with crystalline protection, which could completely change the treatment of diabetes and other chronic diseases.
Liver infected with hepatitis. Illustration: depositphotos.com

When the virus leaves a mark: Epigenetic “stamp” after hepatitis C cure may explain ongoing risk of liver cancer

Research led by Prof. Meital Gal-Tanaami of Bar-Ilan University and supported by the Israel Science Foundation is examining how a virus that remains in the cytoplasm manages to change genetic control in the nucleus, and is attempting to map points of intervention to reduce cancer risk as well.
Dr. Natalia Freund. Photo: Tel Aviv University Spokesperson

A long and winding journey to discover new ways to fight tuberculosis

A study from Tel Aviv University identified two families of human antibodies that bind to the PSTS1 protein of the tuberculosis bacterium, and in a mouse experiment, the antibody treatment led to a 50% reduction in the bacterial load in the lungs.
Lung cancer. Illustration: depositphotos.com

Lung cancer diagnosis accuracy improves with artificial intelligence

New model generates a “map” of biomarkers from a standard staining image, improving prediction of disease course and response to immunotherapy in studies of thousands of patients
Lung on a chip. Illustration: depositphotos.com

“Breathing lung on a chip” from single human cells reveals early stages of tuberculosis

A new model in Science Advances combines lung cells, blood vessels, and immune cells from the same genetic origin, simulates breathing, and shows how early foci of cellular damage are formed during infection with the tuberculosis bacterium.
Prostate cancer. Illustration: depositphotos.com

Making drug resistance a weak point in metastatic prostate cancer

A new computational tool, SpotNeoMet, developed at the Weizmann Institute, detects resistance mutations that recur in many patients and create neoantigens – a possible target for “precision” immunotherapy for broad patient groups
The mechanism that allows breast cancer to metastasize to the brain has been deciphered. Courtesy of the researchers

For the first time, a mechanism that allows breast cancer to metastasize to the brain has been deciphered

Researchers from Tel Aviv University have identified a link between loss of p53 activity (and sometimes deletions in the short arm of chromosome 17) and the adaptation of breast cancer cells to the brain environment through fatty acid pathways and communication with
Heart disease and cancer and drug treatments – interactions

Between the heart and cancer: Technion researchers reveal surprising interrelationships between heart disease and cancerous tumors

Researchers at the Ruth and Baruch Rappaport Faculty of Medicine at the Technion present complex interrelationships between heart disease and cancer, in the hope that the findings will lead to improved treatment of both diseases.
Immune system cells. Illustration: depositphotos.com

Immune cells "caught red-handed" – new clues for early detection and possible prevention of type 1 diabetes

Researchers at the University of Pennsylvania analyzed nearly a million immune cells from organ donors, identified a unique subpopulation of CD4 cells in the lymph nodes of the pancreas and changes in B cells in the spleen, and offer a direction for the development of a simple blood test.
Tel Aviv University's IGEM 2025 team. Photo by Tel Aviv University Spokesperson

Tel Aviv University's IGEM team leads breakthrough in synthetic biology against lung cancer and promotes national high school competition

Along with developing models and software that could transform the study of lung cancer and genetic diseases, Tel Aviv University's IGEM team collaborated with the ORT Network and organized a synthetic biology competition for high school students with the participation of
Microsoft researchers have developed an artificial intelligence system called Cell2Sentence-Scale. Think of it as GPT-chat, but for the language of cells and the molecules they are made of.

Artificial intelligence developed a new hypothesis for treating cancer – and verified it in laboratory experiments

Microsoft's Cell2Sentence-Scale Model Identifies Silmitasertib as a CK2 Inhibitor That Increases Antigen Presentation in "Cold" Cancer Cells – A New Insight Tested in the Lab and Demonstrates AI Research Creativity
Prof. Ronit Saatchi Fainero. Photo: Tel Aviv University spokesperson

Attacking brain tumors

Prof. Ronit Sacchi-Painero identified two key proteins – CCL2 and P-Selectin – that are involved in cancer cell entry into the brain. Blocking either axis significantly reduced metastatic burden in mouse models and in vitro systems.
Dementia. Press releases. Illustration: depositphotos.com

10 Surprising Ways Diabetes and Dementia Are Intertwined

Diabetes affects the brain through energy utilization, blood vessels, and inflammation—and sometimes the same medications work on both systems. Recent studies suggest a mutual connection:
Diabetes. Illustration: depositphotos.com

A new form of diabetes has been officially recognized: Type 5 diabetes.

The new classification refers to diabetes that results from malnutrition in childhood.
Prof. Tal Dvir from the Sagol Center for Regenerative Biotechnology, head of the Nanotechnology Center at Tel Aviv University and chief scientist of the biotech company Trisself. Photo: Tel Aviv University Spokesperson

Tel Aviv University researchers have developed a human spinal cord implant that allows paralyzed people to regain movement

A team led by Prof. Tal Dvir has succeeded in growing a customized spinal cord transplant from the patient's own cells. After success in animals, the Ministry of Health has approved the first human trial in Israel.
From right: Dr. Naama Darzi, Prof. Ayelet Erez, Dr. Natalie Rosenfeld and Dr. Elizaveta Bab-Dinitz. Photo by Weizmann Institute Spokesperson

It's all in the head: Blocking the communication channel between the brain and liver may prevent life-threatening weight loss in cancer patients

Research at the Weizmann Institute of Science demonstrates how communication between the brain and the body's organs plays a critical role in health and disease
Bandages may now be smart. Illustration: depositphotos.com

New bioactive dressing promises faster healing for diabetic wounds

Researchers have developed an innovative bandage that combines biologically active substances, which helps accelerate wound closure and prevent infections – with the potential to significantly improve the quality of life of those with diabetes.
Immune system cells attack a cancer cell. Illustration: depositphotos.com

The gene that maximizes sunlight – and may eliminate cancer cells

Scientists have discovered that SDR42E1, a tiny gene linked to vitamin D absorption, could be the key to treating cancer: When it was turned off in cancer cells, the tumor stopped growing.
Comparing digestive systems: men versus women in models built in the Lezmas Laboratory. Courtesy of the Technion

The stomach speaks differently: Men and women digest milk differently

Technion researchers have discovered that biological sex (or gender) affects the efficiency of digesting milk and its substitutes – a finding that may change perceptions of nutrition and food engineering.
The system was developed by the research group led by Prof. Hosem Haik. Credit: Xia Gong

New wearable system for real-time diabetes monitoring

Joint development by Prof. Hussam Hayek from the Technion and researchers from Sun Yat-sen University enables glucose measurement and personalized metformin dosing using microneedles and nanobiological sensors
An Egyptian mummy excavated from the tombs of the pharaohs. Illustration: depositphotos.com

The mold that caused the curse of the pharaohs becomes a weapon against leukemia

Scientists have managed to engineer compounds from the mold Aspergillus flavus that defeat leukemia cells – signaling hope for new drugs from nature
Leukemia. Illustration: depositphotos.com

The blood test that will identify the risk of leukemia – and may replace bone marrow aspiration

Just days after their laboratories were damaged in an Iranian attack, Prof. Liran Shlush and Prof. Amos Tanai publish groundbreaking findings that are expected to advance the field of blood cell medicine.
Risk factors for high blood pressure. Illustration: depositphotos.com

New drug could help millions of people with high blood pressure

A new injection, given twice a year, could revolutionize blood pressure treatment and prevent major cardiovascular events.
3D model of the human heart with blood flow analysis and anatomical aspects. Photo courtesy - Dassault Systèmes

Dassault Systèmes launches beta trial for customized living heart model

A new 3D model for creating “virtual twins” of patients and populations – an automated tool for research and development of medical devices and treatments
Two human heart models, one simulating a healthy heart and the other a diseased one. Photo: Dassault Systèmes

Members of the "Living Heart" project are testing a new generation of a customizable model

Dassault Systèmes enters the next phase of the "Living Heart" project with AI-based virtual twinning * Matching and automation of virtual models of the heart, based on AI, will help simplify and accelerate
Intra-abdominal fat. Illustration: depositphotos.com

New study reveals: The link between intra-abdominal fat and metabolic risk

Comprehensive research by Ben-Gurion University and international partners indicates the importance of reducing intra-abdominal fat for improving metabolic health, even with moderate weight loss.
A microscopic image of tissue stained in purple, red, and green to identify various cellular components.

Two ways to a broken heart, two ways to heal

Illustration: depositphotos.com

"The Early Warning Signs of Cancer: Epigenetic Discoveries That Inspire Hope"

New study reveals that cancer risk may be determined before birth, suggesting new directions for diagnosis and treatment
Minister of Science and Technology Gila Gamliel and the head of the Isfaia Local Council, Munib Sabaa. Photo: Idan Media, for the Government Advertising Bureau

Oral bacteria linked to increased risk of stroke

The lead researcher from the National Heart Disease Center in Osaka, notes: "In the future, if a rapid test is developed to identify harmful bacteria in the mouth and intestines, we could use this information to calculate stroke risk."
Transporting medicines. Illustration: depositphotos.com

Innovative technology for biological nanoparticles enables combined treatment against cancerous tumors

Researchers from Tel Aviv University have developed an innovative platform based on nanoparticles, which enables the precise transport of two drugs at the same time to cancerous tumor sites, while improving treatment efficiency and reducing toxicity to healthy cells.
Ground level ozone has negative effects on human health. Photo: pexels, german latasa

How does ozone pollution affect diabetes morbidity?

Heart attacks happen at night. The image was prepared using DALEE and should not be considered a scientific image.

Why do more heart attacks and asthma occur at night?

Weizmann Institute of Science scientists have discovered why the small hours of the night may be prone to disaster
Starving cancer through sugar deprivation. The image was prepared using DALEE and is not a scientific image

Breakthrough in brain cancer treatment: starving cancer cells causes them to burn themselves

The D'20 peptide inhibits the cancer-causing enzyme MMP7. The image was prepared using DALEE and is not a scientific image

A new stable and selective inhibitor of a cancer-causing enzyme has been revealed in a new study

Researchers from the Hebrew University, the Weizmann Institute and the University of Tokyo have developed an innovative peptide that suppresses the activity of the MMP7 enzyme associated with cancer progression, with the potential for targeted therapies in aggressive cancers.
Lung cancer. Illustration: depositphotos.com

A new blood test for the early detection of tissue damage caused by cancer treatments

A method developed at the Hebrew University allows early detection of lung damage among cancer patients receiving antibody-based treatments, using a simple non-invasive blood test
Fruit flavored electronic cigarettes are dangerous. can cause lung cancer and other diseases. The image was prepared using DALEE and is not a scientific image

A new study in PNAS reveals that fruit-flavored e-cigarettes harm the immune system of the lungs

The Cancer Society: "The reason for using sweet flavors is an attempt to bring teenagers into the circle of users. Their sale must be banned immediately"
Section of breast tissue from a triple negative breast cancer (TNBC) patient, on the right, and healthy breast tissue, on the left. In the cancer patient, the cancer cells (indicated in light blue) surround cells in their microenvironment that express a high level of CD84 (indicated in purple)

burn the bridges of cancer

The institute's scientists revealed how aggressive breast cancer disrupts the immune response against it, and developed a treatment using an antibody that may be suitable for many types of cancer
Prof. Carmit Levy and Prof. Yaron Carmi

Researchers from Tel Aviv University have discovered a new cancer mechanism, the activation of which eliminates cancerous tumors

Prof. Carmit Levy: Immunotherapy has revolutionized cancer treatment," explains Prof. Carmi, "but about 50% of patients do not respond to the standard treatment - the PD-L1 protein. We found a new protein Ly6a against which treatment with an antibody
A sample from a tumor of a human patient with the most common lung cancer (adenocarcinoma). The presence of senescent cells expressing the proteins P16 (in red) and PD-L1 (in green) can be detected. The cell nuclei in the sample are marked in blue

to open blockages in the immune system

Heart Attack. Illustration: depositphotos.com

Discovery of violations

Copaxone may protect heart muscle cells and improve its function after a heart attack
The layers of glioblastoma tumors: first layer of necrotic tissue in the center of the tumor that does not receive oxygen supply (red), second layer of cancer cells that mimic fetal connective tissue (yellow), third layer of immune cells (green) and blood vessels (white) and fourth layer of tumor cells that receive oxygen and imitate normal tissues in the brain (in pink and light blue)

peel back the layers from the brain tumors

In two recently published studies, Weizmann Institute of Science scientists mapped common brain cancer tumors with unprecedented resolution, and identified a possible reason why some patients do not respond to a new treatment
cancer cell Illustration: depositphotos.com

What predicts your cancer type?