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the cell

The Israeli delegation (from right to left): Yara Shulman, Tamar Farr, Nega Friedman and Nicole Grossman. Photo: Future Scientists Center

European Mathematics Champions

Students trained at the Weizmann Institute won the gold and silver medals in the European Mathematics Olympiad for Girls
The triple strategy of the corona: 1. A general decrease in the translation products in the cell; 2. Breakdown of messenger RNA molecules of the cell; 3. Preventing the exit of messenger RNA molecules from the nucleus

The triple of the corona

The scientists of the Weizmann Institute of Science, in partnership with the scientists of the Biological Institute in Nes Ziona, revealed how a unique combination of three mechanisms allows the corona virus to escape the immune system
cells in a petri dish. Photo: depositphotos.com

TA researchers disproved a theory about the role of COPII proteins inside the cell

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A XNUMXD model of a network of photosynthetic membranes in a plant, based on electron microscope photographs. Thylakoids (in yellow) are surrounded by parking garage-like structures, consisting of ramps curving to the left (in purple) and to the right (in blue)

Park with minimal effort

How parking lot-like structures are organized that are used to transport substances within the cell
Avocado. Photo: depositphotos.com

A natural food supplement may act as an anti-anxiety agent

Weizmann Institute of Science scientists have shown that the herbal supplement reduces anxiety levels in mice without significant side effects
Mouse brain section. The parts illuminated in red - communication pathways between nerve cells that express the mosquito protein. In blue - the cell nuclei

Mosquito on the head

Weizmann Institute of Science scientists have developed a research tool that will shed new light on communication pathways between nerve cells in the brain
From the right: Prof. Eli Waxman and Prof. Avishai Gal-Yam

A star dies, a particle is born

Is the origin of a particle that landed at the South Pole in a cosmic event 700 million years old?
Measuring heart muscle cell beats for a few minutes (left) does indeed reveal deviations from the ideal beat rhythm - a beat every second - but when this is done over several hours (right) a new pattern is revealed: slower or faster than average beats that appear in clusters of 10 to 30 minutes

The strange dance of the heart

Scientists at the Weizmann Institute and the Technion have discovered clues to the existence of a slow regulatory mechanism in heart muscle cells designed to regulate the rhythm of their beats, and to ensure that it is as close as possible to a cycle of one beat per second
4D structure of the stemalnotide drug molecule (pink) and calcium ion (green) in the binding pocket of the MCXNUMX receptor

The Hunger Games: the mechanism of action of the switch in the brain responsible for the feeling of satiety

Understanding the mechanism is expected to help in the development of new anti-obesity drugs
Neurons of a mouse under a microscope. An inhibitory neuron (right) and an excitatory neuron (left)

Keep a balanced mind

Networks of nerve cells grown in the laboratory revealed a new regulatory mechanism that maintains a balance between activation and suppression of brain activity
DNA molecule. Image: depositphotos.com

The loom of evolution

A new method makes it possible to locate points of similarity between gene control molecules of different species - from lizards to humans - and thus reveal essential sections that have been preserved throughout evolution
Micro-reservoirs of lipid assemblies (liposomes) dispersed in the bulk of the gel - the diameter of the smallest ones is about 100 nanometers

Inspirational cartilage

Weizmann Institute scientists have created innovative materials inspired by the lubrication model of our joints. The result may be real news for the biomedical industry
A mouse fetus grown six days outside the womb. His developing organs were marked with fluorescent genes

Weizmann Institute scientists grew mouse embryos outside the womb

For seven years, through trial and error, fine-tuning and repeated tests, in the laboratory of Prof. Hana, who specializes in embryonic stem cells, they developed a two-stage method that makes it possible to grow normal mouse embryos outside the womb from the initial stages of pregnancy in order to study the different stages of development of the embryo, Something that was not possible in mammals until now
Imaging of a ring-shaped malaria parasite that lives inside a red blood cell and secretes vesicles carrying the S20 proteasome (colorful barrel-like structures)

kills them softly

A model of the translating ribosomes and the elongation factors. The localized accumulation of translation factors contributes to efficient protein synthesis within a dense intracellular environment.

High-speed atomic force microscopy reveals the components of the ribosome

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The researchers conclude and say: "Future research using high-speed atomic force microscopy (HS-AFM) will provide additional important information for understanding the dynamic activity of these complex translation machines."
Corona virus attacks the lung cells. Image: depositphotos.com

Israeli researchers succeeded in deciphering the structure and activity of three SARS-COV-2 proteins

One of the largest proteins of the virus, which the researchers were able to decipher using a new and unique method, is a protein called Nsp2, known as "reluctant" to structural decipherment. Dr. Dina Schneidman: "We now have technology and an experimental protocol to study not only the virus proteins themselves, but also their partners inside the human cell"
Drug-resistant cells of multiple myeloma (purple-blue) under a microscope. The laboratory of Prof. Ido Amit, Weizmann Institute

A genetic signature of drug resistance in multiple myeloma blood cancer has been revealed

From the patient's bed to the laboratory and back: collaboration between the institute's scientists and doctors in Ichilov may lead to personalized treatments for multiple myeloma patients, who do not respond to drugs - and paves the way for personalized treatments in other types of cancer
The lining of the large intestine of a mouse under a microscope. The mucosa of normal mice (top, left) malfunctions as inflammation progresses (top, middle) and promotes the development of cancer (top, right). In contrast, in mice without HSF1 (bottom, left), inflammation does not develop (bottom, middle and right)

A slippery and inflamed slope

The anatomy of the cells in the human body. Photo: depositphotos.com

The revolving door of the cells

Weizmann Institute of Science scientists have mapped the rate of regeneration of our body * Every year and a half we produce 50 kilograms of cells, as the average weight of the cells in our body
A swarm of hexagons is crushed into a passing car. Photo: shutterstock

The humming of the tentacles' inclusions

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The tentacles, relatives of the mosquitoes, have a strange wedding custom, they choose their spouse in a huge swarm of tentacles and yet continue to stick together. A new study managed to decipher the phenomenon
Cell membrane receptors. Photo: depositphotos.com

A new computational method significantly shortens the process of identifying receptor roles

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Since most of the drugs today work by activating or blocking receptors, the new method has the ability to significantly shorten the drug production process
Micro RNA. Illustration: Prof. Robert Johnson, Temple University

Deepening our knowledge in understanding the RNA molecule allowed us to produce a rapid vaccine for Corona

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This is according to the decision of the Wolf Prize Committee for 2021 in medicine. The judges' announcement stated that these scientists made breakthrough discoveries in the mechanisms that regulate RNA and demonstrated that RNA is not a passive template between DNA and protein but plays a dominant role in regulating and diversifying genetic expression
Horizontal gene transfer. The genetic information is transferred between individuals who are not related to each other and can even belong to another species

Lateral transfer of genes: in the evolution test copying is allowed

Through "evolution in vitro" experiments, Weizmann Institute scientists have shown what happens when bacteria copy genetic information from their neighbors
Prof. Nir Friedman. Courtesy of the Hebrew University

A method for diagnosing a wide variety of diseases by a simple blood test instead of invasive tests

The changes in the sex hormone testosterone in men throughout the year, based on about 130 thousand samples

Four Seasons Hormone

Analysis of millions of Israelis' blood tests reveals hormonal fluctuations affected by the calendar
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