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Promising drugs for diabetes

Beata, an innovative injectable treatment for diabetics, encourages the production of insulin in the pancreas

Four new drugs to treat diabetes raise hopes among doctors and patients alike. The new drugs work differently and more effectively than existing drugs, and their side effects are milder. One of the four, byetta, marketed in the US since June 2005, is given by self-injection, and it encourages the pancreas to produce more insulin and the liver to produce less blood sugar. It results in significant weight loss, unlike existing diabetes medications that sometimes cause obesity, a development that exacerbates the disease.

Another innovative drug is Exubera, it is an inhalable insulin, and it is supposed to go on the market in the US in July. The other two drugs, Galvus and Januvia, are pills that encourage the production of the hormone 1-GLP, which in turn encourages the pancreas to produce more insulin and the liver to produce less blood sugar. They are supposed to go on the market in the USA at the end of 2006 or at the beginning of 2007. Doctors who participated in the development of the new drugs say that with these drugs control of the disease will be achieved in about 90% of the patients.

Patients with type 2 diabetes (adult-onset diabetes) gradually lose the ability to produce insulin, a hormone secreted by the pancreas that controls the blood sugar level, at the same time the resistance in their body to the insulin that their body still manages to produce increases.

New York Times
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