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Alon Chen

An oligodendrocyte-type cell with many of its branches (in yellow) in a mouse brain section. Reacts to stress quite differently in males and females

Exposure to chronic stress activates different cells in the brains of females and males

From depression and anxiety to diabetes - health conditions resulting from chronic stress affect women and men differently. New study in mice maps at the single-cell level molecular differences in the stress response in the brains of females and males, and may pave the way for personalized treatments
The "love hormone" or the "social hormone"?

The "love hormone" may also cause anxiety and aggression

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A section of a mouse brain showing the expression of the ASL enzyme (in purple) in the brainstem region called the locus coeruleus. The laboratory of Prof. Ayelet Erez, Weizmann Institute

On the way to the brain, we stop at the liver

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Four mice in an equipped cage exhibit 60 different behaviors to be evaluated. The laboratory of Prof. Alon Chen, Weizmann Institute

Character of a mouse: Weizmann Institute scientists have developed a personality test for animals

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Prof. Alon Chen. Photographer: Axel Gerish

Prof. Alon Chen was elected the next president of the Weizmann Institute of Science

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A mouse embryo and the genetically engineered placenta that feeds it. programmed for anorexic behavior. Photo: Weizmann Institute

programmed from birth

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depression. Illustration: shutterstock

A molecule that may enable the diagnosis and development of advanced and effective drugs for the treatment of depression, anxiety, and other mental disorders

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Medicines. Illustration: shutterstock

Small molecules, big hopes

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Mouse hypothalamic neurons expressing leptin receptors

It's in our heads

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Coloring of the meeting areas between nerve cells (green) and muscle (red). The yellow staining represents complete overlap between the nerve cells and the muscle in normal mice (bottom). In transgenic mice, which lack microRNA in nerve cells that innervate muscles, only the muscle staining is visible (above, in red), because the nerve in the junction area is diseased. Illustration: Weizmann Institute

ALS - suddenly in the middle of life

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The motor neurons, which control voluntary muscle movement, gradually degenerate. As a result, the patient loses the function of most muscles
Diet chocolate but delicious from Germany. Photo: Avi Blizovsky

A gene that links stressful situations with obesity, diabetes and other metabolic diseases

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