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Weizmann Institute

Drug-resistant cells of multiple myeloma (purple-blue) under a microscope. The laboratory of Prof. Ido Amit, Weizmann Institute

A genetic signature of drug resistance in multiple myeloma blood cancer has been revealed

From the patient's bed to the laboratory and back: collaboration between the institute's scientists and doctors in Ichilov may lead to personalized treatments for multiple myeloma patients, who do not respond to drugs - and paves the way for personalized treatments in other types of cancer
The lining of the large intestine of a mouse under a microscope. The mucosa of normal mice (top, left) malfunctions as inflammation progresses (top, middle) and promotes the development of cancer (top, right). In contrast, in mice without HSF1 (bottom, left), inflammation does not develop (bottom, middle and right)

A slippery and inflamed slope

The anatomy of the cells in the human body. Photo: depositphotos.com

The revolving door of the cells

Weizmann Institute of Science scientists have mapped the rate of regeneration of our body * Every year and a half we produce 50 kilograms of cells, as the average weight of the cells in our body
A swarm of hexagons is crushed into a passing car. Photo: shutterstock

The humming of the tentacles' inclusions

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The tentacles, relatives of the mosquitoes, have a strange wedding custom, they choose their spouse in a huge swarm of tentacles and yet continue to stick together. A new study managed to decipher the phenomenon
Horizontal gene transfer. The genetic information is transferred between individuals who are not related to each other and can even belong to another species

Lateral transfer of genes: in the evolution test copying is allowed

Through "evolution in vitro" experiments, Weizmann Institute scientists have shown what happens when bacteria copy genetic information from their neighbors
The changes in the sex hormone testosterone in men throughout the year, based on about 130 thousand samples

Four Seasons Hormone

Analysis of millions of Israelis' blood tests reveals hormonal fluctuations affected by the calendar
As we add ingredients to a fruit smoothie, it will be difficult to put our finger on the contribution of each ingredient to the final result. A fruit salad, on the other hand, allows you to combine flavors without masking the unique contribution of each fruit. Similarly, when checking the average gene expression in a certain tissue (left), it is not possible to distinguish the differences between different cells in the same tissue. Technological developments of recent years make it possible to measure the expression of genes in a tissue at the level of the single cell (right), thus characterizing with unprecedented resolution differences between cells in the same tissue

Each and every cell is stressed: first mapping of the "stress axis" at the individual cell level

From the brain to the adrenal glands - scientists from the Weizmann Institute of Science and the Max Planck Institute have mapped the entire "stress axis" and shown how chronic stress affects and changes these tissues at the individual cell level. The scientists discovered a new subpopulation of endocrine cells involved in regulating the response to chronic stress
Excavations in the volcanic ash in Santorini. Photo: shutterstock

A volcano, an atomic bomb and an olive branch

Illuminated effect: two fine gratings, almost identical, provide high measurement sensitivity - and the coarse grating created by the overlap between them makes it possible to increase the dynamic range. Weizmann Institute

At sea, in the air and on land - atomic navigation is gaining momentum

Innovative navigation technologies that do not depend on cellular or satellite communication, rely on measuring the acceleration of atoms using cold atom interferometers. Recently, Weizmann Institute scientists have increased the measuring range of these devices a thousandfold
Liron Grover and Prof. Ehud Ahisher. with a sensitive eye. Weizmann Institute spokeswoman photo

Eyes closed

Mouse brain tissue. The octopus-like microglial cells are marked in red. In green - blood vessels. Courtesy of the Weizmann Institute

calm the microglia in the brain

In degenerative brain diseases, Alzheimer's for example, there is an overactivity of the representatives of the immune system in the brain. Weizmann Institute of Science scientists have revealed the mechanism that allows these cells to return to normal
blindness. Photo: depositphotos.com

Phantom vision: a brain mechanism that allows the blind to see in their mind's eye

Charles Bona syndrome, blindness, Rafi Malach, Weizmann Institute
speed of light. Illustration: depositphotos.com

Yes, break the speed of light

On time, message transmission and quantum phenomena
Huge waves. Illustration: depositphotos.com

Each wave carries a souvenir (from another wave)

Plastic waste on the beach. Illustration: depositphotos.com

Light and indestructible: the plastic particles that are carried by the wind and we breathe

Prof. Ilan Koren: "Even if we stop polluting the beaches tomorrow morning, we are expected to see more and more microplastic particles emitted into the atmosphere - since it takes time for the plastic waste that has already found its way to the sea to break down into particles"
T cells of the immune system attack a cancer cell. Illustration: shutterstock

Cancer cells' secret recipe for protein production may become a weapon against them

The findings of the research findings are presented graphically and tangibly on a website dedicated to the public, created by the scientists in collaboration with the designer Itay Reva. To the website To the website Illustration: Itai Ravehkar are presented graphically and tangibly on a dedicated site open to the public created by the scientists in collaboration with the designer Ai Raveh. Click on the image to go to the website. Illustration: Itai Rava

The globe of concrete

During 2020, human products exceeded the mass of all life in our world. ​The mass of buildings, cars and bottles doubles every 20 years - and the curve is about to flatten
A helical lock (orange) on the DnaJB1 chaperone blocks the binding site for chaperones from the Hsp70 family

Overcome the precipitation

The discovery of a mysterious helical lock may shed light on the development of degenerative brain diseases
An eye of a fruit fly engineered to develop an ALS-like disease. Left: Defective protein aggregates leading to ALS-like degeneration. Right: the eye returned to normal following the expression of one of the "sumo" proteins

Heavy weight pellets

Weizmann Institute of Science scientists deciphered the molecular mechanism of "return to normal" and discovered that it is based on labeling proteins for destruction with a special code known as "SUMO"
differences between the sexes. Illustration: depositphotos.com

Differences between the sexes - the worm version

Recently, Weizmann Institute of Science scientists compared neural networks of female and male worms, and discovered a molecular mechanism that may explain how differences between the sexes in neurological diseases in humans arise
Odors may be measured by their distance from each other. Prof. Noam Sobel's laboratory, Weizmann Institute

The smell index: a new method makes it possible to accurately measure similarity between smells

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The development by Weizmann Institute of Science scientists makes it possible to predict what the smell of any molecular compound will be and may pave the way for the digitization and reproduction of smells
Creative thinking. Illustration: shutterstock

The human mind presents: organized noise is the father of invention

A new study by Weizmann Institute of Science scientists offers an explanation for these magic moments, when new ideas sprout in us
Bacteriophage - a virus that attacks bacteria. Illustration: Illustration: depositphotos.com

A mysterious component in bacteria has been discovered as a last line of defense against viral infection

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Besides solving a 36-year-old mystery, Weizmann Institute of Science scientists have identified thousands of types of these components, which may be used in gene editing
cancer cell Image: Shutterstock

The memories of a cancer cell

A group of scientists at the Weizmann Institute of Science recently investigated what happens to cellular memory in cancer. Their findings illustrate how "memory loss" may affect the course of malignant diseases
Mouse liver tissue under the microscope. Signs of acute liver failure (left) disappeared after administration of a drug that blocks the control protein MYC

Involvement of intestinal bacteria and liver cells in acute liver failure

Weizmann Institute of Science scientists revealed the discovery and outlined a path for future treatment
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