MTCH2

Get rid of the fat and lose weight

Weizmann Institute of Science scientists reveal how the mitochondrial protein Mitch affects obesity and muscle endurance, potentially paving the way for an improved weight loss drug that doesn't have the drawbacks of Ozempic
Decreased mitochondrial calcium uptake in cells where the MTCH2 gene has been neutralized. The photo on the left shows a nerve cell that has not been genetically modified. The photo on the right shows a transgenic nerve cell (without MTCH2). Fluorescent sensors were inserted into the cells in order to illuminate the absorption of calcium in the mitochondria, and calcium was added to the growth medium of the cells. As you can see, the sensors illuminate significantly less in the engineered cell (the color scale ranges from blue, indicating low calcium absorption, to yellow, indicating high calcium absorption), which indicates impaired calcium absorption in the mitochondria. Source: from the article.

calcium escape from the brain