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Aging cells

Transient aging: Zebrafish (top row), newborn mouse (middle row) and adult mouse (bottom row) hearts are seen (left column) with almost no senescent fibroblasts (indicated in turquoise). After injury to the heart muscle (accompanying agrin injections in an adult mouse), many fibroblasts went into a state of senescence (middle column), which passed about three weeks later (right column)

Aging cells, young heart

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