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Degenerative brain diseases

Microglial cells that were "ripened" in the laboratory from stem cells derived from ALS patients (in green), the cell nuclei - in blue. Photographed using a confocal microscope

The good mutation

Weizmann Institute of Science scientists have discovered a new pathway that may protect nerve cells in the brain and slow down the development of degenerative brain disease
An eye of a fruit fly engineered to develop an ALS-like disease. Left: Defective protein aggregates leading to ALS-like degeneration. Right: the eye returned to normal following the expression of one of the "sumo" proteins

Heavy weight pellets

Weizmann Institute of Science scientists deciphered the molecular mechanism of "return to normal" and discovered that it is based on labeling proteins for destruction with a special code known as "SUMO"
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