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pressure

An oligodendrocyte-type cell with many of its branches (in yellow) in a mouse brain section. Reacts to stress quite differently in males and females

Exposure to chronic stress activates different cells in the brains of females and males

From depression and anxiety to diabetes - health conditions resulting from chronic stress affect women and men differently. New study in mice maps at the single-cell level molecular differences in the stress response in the brains of females and males, and may pave the way for personalized treatments
Illustration: depositphotos.com

Channels deep in the ground could be the key to habitability on Mars

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The Bio-SPHERE project investigates potential living and working conditions on the Moon and Mars
Microglial cells (in green) in the hippocampus region of the brain of an adult mouse, forming contact points with a new neuron (in red)

The biology of depression

Degeneration of the cells of the immune system in the brain may be the biological cause of depression, and there may be substances that can restore these cells - and be antidepressants
As we add ingredients to a fruit smoothie, it will be difficult to put our finger on the contribution of each ingredient to the final result. A fruit salad, on the other hand, allows you to combine flavors without masking the unique contribution of each fruit. Similarly, when checking the average gene expression in a certain tissue (left), it is not possible to distinguish the differences between different cells in the same tissue. Technological developments of recent years make it possible to measure the expression of genes in a tissue at the level of the single cell (right), thus characterizing with unprecedented resolution differences between cells in the same tissue

Each and every cell is stressed: first mapping of the "stress axis" at the individual cell level

From the brain to the adrenal glands - scientists from the Weizmann Institute of Science and the Max Planck Institute have mapped the entire "stress axis" and shown how chronic stress affects and changes these tissues at the individual cell level. The scientists discovered a new subpopulation of endocrine cells involved in regulating the response to chronic stress
An eye of a fruit fly engineered to develop an ALS-like disease. Left: Defective protein aggregates leading to ALS-like degeneration. Right: the eye returned to normal following the expression of one of the "sumo" proteins

Heavy weight pellets

Weizmann Institute of Science scientists deciphered the molecular mechanism of "return to normal" and discovered that it is based on labeling proteins for destruction with a special code known as "SUMO"
anxiety. Illustration: shutterstock

The closure caused a structural change in the areas of stress and anxiety in the brain

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This is according to a study by Tel Aviv University. Before and after the first lockdown, the researchers scanned the brains of 50 healthy subjects in their 30s who had not contracted the corona virus. The results indicate an increase, among other things, in the volume of the amygdala - an area of ​​the brain responsible for emotional regulation
Roach. From Wikipedia

Cockroaches - from all my educational teachers (not for the faint of heart)

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The cover of Neuron magazine from February 2012, with an article by researchers from the Weizmann Institute on the body's function in stressful situations

Editing under pressure

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Alon Chen and his lab team. Photo: Weizmann Institute

Get out of the pressure

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Do the cores of the giant planets contain diamonds?

Rahab Diamonds

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Research at the Hebrew University: Women cope better with stress compared to men

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Doctors are also forced out of work under the threat of missiles

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From the brain to the body - why do we get sick in stressful situations?

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