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Pituitary gland

The pituitary gland of the zebrafish. The variety of cell types are marked in different colors: in purple - phytocytes, in red and green - two types of hormone-producing cells

Where does the fish secrete from: back to the origins of the pituitary gland

Weizmann Institute scientists are challenging a 200-year-old doctrine about the formation of the gland from the secretion of hormones. Their findings may lead to new approaches in the treatment of various medical problems
As we add ingredients to a fruit smoothie, it will be difficult to put our finger on the contribution of each ingredient to the final result. A fruit salad, on the other hand, allows you to combine flavors without masking the unique contribution of each fruit. Similarly, when checking the average gene expression in a certain tissue (left), it is not possible to distinguish the differences between different cells in the same tissue. Technological developments of recent years make it possible to measure the expression of genes in a tissue at the level of the single cell (right), thus characterizing with unprecedented resolution differences between cells in the same tissue

Each and every cell is stressed: first mapping of the "stress axis" at the individual cell level

From the brain to the adrenal glands - scientists from the Weizmann Institute of Science and the Max Planck Institute have mapped the entire "stress axis" and shown how chronic stress affects and changes these tissues at the individual cell level. The scientists discovered a new subpopulation of endocrine cells involved in regulating the response to chronic stress
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