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epigenetics

Canaanite finds from Megiddo Hill (courtesy of Megiddo Archaeological Expedition)

Researchers have analyzed the genetics of the Canaanites and its relationship to modern populations such as Jews, Palestinians and Bedouins

The DNA analysis showed that the Canaanites were created from the mixing of populations that migrated to the southern Levant mainly from the Caucasus region (or western Iran) with ancient local populations that stayed there, a process that lasted at least 1,000 years
Histological sections of the leg muscles without injury (left) and five days after it (center, right) in a control mouse and a transgenic mouse. It can be seen that the area of ​​the muscle fibers that develop after the injury is smaller in the transgenic mouse, which indicates a disturbance in the differentiation of the stem cells into muscle cells

overcome the damage

Researchers have discovered that two epigenetic events (removing and adding methyl from DNA) lead to the differentiation of stem cells into muscle cells and thus to the regeneration and healing of muscles after their injury
Mouse brain section. The parts illuminated in red - communication pathways between nerve cells that express the mosquito protein. In blue - the cell nuclei

Mosquito on the head

Weizmann Institute of Science scientists have developed a research tool that will shed new light on communication pathways between nerve cells in the brain
mildew. Illustration: depositphotos.com

The surprising genetic evolution of ancient plants

cancer cell Image: Shutterstock

The memories of a cancer cell

A group of scientists at the Weizmann Institute of Science recently investigated what happens to cellular memory in cancer. Their findings illustrate how "memory loss" may affect the course of malignant diseases
epigenetics. Illustration: shutterstock

Three laws that dictate intergenerational epigenetic inheritance - not through changes in the DNA sequence

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Prof. Oded Ravavi's laboratory previously discovered that worms bequeath to their offspring small RNA molecules that contain information about the parents' environment, such as nutritional status, viral infection and even the brain activity of the parents, thus contributing to the survival of future generations. In their current study, Prof. Ravavi and his team tried To understand whether there are laws for the epigenetic inheritance of small RNAs over the generations or whether it is a passive and random inheritance
The evolution within the evolution. Illustration: Maya Shleifer

The evolution within the evolution

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Diagram of the spatial interaction between the DNA control regions and the controlled genes. The "reporters" (in red and green) reveal these interactions. The laboratory of Dr. Yonatan Stanzler, Weizmann Institute

A cell following its fate

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From the right: Dr. Ronit Nir, Ran Shahar, Miguel Engel Garcia-Campos, Dr. Modi Safra, Dr. Sharit Adelheit-Flor and Dr. Shraga Schwartz. There are many tags in the cell. Photo: Weizmann Institute Spokesperson

The golden tag: How does the m6A chemical tag involved in the control of the human genome work?

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A family tree of worms, based on a neuron (nerve cell), and RNA molecules that transmit information between generations. Credit: Beata Edyta Mierzwa

A mechanism has been deciphered that allows the inheritance of brain activity from generation to generation - not through DNA

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Embryonic stem cell colonies as seen under a microscope: the cells differentiated in an orderly manner when their genome contained a normal copy of the p53 gene (left), but not when p53 was missing (right). Source: Weizmann Institute magazine.

The new role of the guardian of the genome

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Epigenetics - illustration: shutterstock

Researchers from Tel Aviv University have revealed laws that dictate epigenetic inheritance other than through DNA

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Illustration of DNA being transported through a nanometer pore. Courtesy of Prof. Amit Meler, Technion

Beyond the sequence

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A centriole as photographed with an electron microscope. Photo: © Pierre Gönczy/EPF

Beyond genes: do centrioles carry biological information?

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Prayer for the healing of a terminally ill patient. Illustration: shutterstock

On New Age "science".

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identical twins. Photo: shutterstock

What makes some identical twins look different from each other?

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Three chromosomes 21 instead of two in Down syndrome patients. Illustration: shutterstock

Scientists have demonstrated the ability to silence the redundant chromosome responsible for Down syndrome

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An adult fruit fly exposed to an environmental challenge (poison) during its development (left), compared to a fly that developed in a favorable environment (right)

challenges in the environment

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From the right: Alina Molchedsky, Gilad Landan, Naomi Goldfinger, Dr. Zohar Mochmal, Prof. Verda Rutter, Netta Mendelson Cohen, Dr. Amos Tanai and Amir Bar. adolescence

Epigenetics: It all depends on education

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The experimental system: two nostrils from which exit ultrasonic beams of excited helium atoms (in blue) and of argon atoms or hydrogen molecules (in red). The blue beam passes through a magnetic device (in yellow) which causes it to bend, and merges with the red beam - then the argon atoms or hydrogen molecules undergo ionization, and enter the detector. The picture above shows a cross-section of the magnetic device

expression and control

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Chimpanzee and man. From Wikimedia - CC license

The human is "allowed" from the chimpanzee - cancer and autism

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Prof. Haim Sider, Hebrew University

Spotlight: Epigenetics - heredity not only in genes / Dorit Ferns

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Epigenetics, from the website integratedhealthcare.eu

Epigenetics: the hidden switches of the mind / Eric J. Nestler

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A rat in London. Photo: from Wikipedia

Rats exposed to stress during childhood passed on the effects of this early exposure to their offspring

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An autistic boy who arranged his toys in a straight line. From Wikipedia

On the genetics of autism

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