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Targeted cancer treatment is worth its weight in gold

Gili Bisker, PhD student in nanotechnology at the Technion and laureate of the UNESCO-L'Oréal Prize for Women in Science develops during her PhD a method for the controlled release of a drug using gold nanoparticles and short laser pulses

From the right - the winners: Gili Bisker, Dr. Efrat Shema-Yacubi and Esnat Sommer-Penn From the right: Prof. Ruth Arnon, president of the Israel Academy of Sciences and winner of the L'Oréal-UNESCO Award for Women in Science Gili Bisker. Photo: Lem Welitz Studio
On the right is Prof. Ruth Arnon, president of the Israel Academy of Sciences and winner of the L'Oréal-UNESCO Prize for Women in Science Gili Bisker. Photography: Lem Welitz Studio

One of the studies that demonstrates how multidisciplinary scientific work in the field of nanotechnology works, in this case at the Russell Berry Institute for Nanotechnology at the Technion, is the research of Gili Bisker, who develops
Her PhD is a new method of cancer treatment in the laboratory of Dr. Dvir Yelin.

Bisker is one of the winners of the UNESCO-L'Oréal Prize for Women in Science, and unlike the other two, she is still in the final stages of her doctoral thesis, and is now looking for a postdoctoral supervisor.
In a conversation with the science website, Bisker explains: "The method is based on the controlled release of drugs from gold nanoparticles using short pulses of a laser. What is good about this method is that it is possible to specifically damage the cancer cells without causing damage to the healthy cells."

"We used the special optical properties of gold nanoparticles that, in their interaction with the laser radiation, increase the intensity of the laser in their immediate environment. You can use the amplification effect to release molecules that were previously attached to the particles and in addition, increasing the power of the laser also has a destructive effect on the cell membrane to which the particle is attached - a cancer cell.

"There is a double effect here, following the laser illumination, the increase in intensity near the particle directly damages the cell's membrane and thus causes the cell to die, and at the same time the same illumination causes the release of the drug molecules that coat the particle and those molecules can mark additional cancer cells in the environment and signal the immune system to eliminate those marked cells by the drug molecule.”

"The research was done as part of the inter-unit program for nano sciences and nano technology in the laboratory of Dr. Dvir Yelin, in collaboration with Dr. Daniela Yehezkali-Hayon and Dr. Limor Minai, and the research is a clear example of multidisciplinary research. We use the optics of lasers from the field of physics, from the field of chemistry we bring the process of producing particles and coating them with drug molecules, and of course we also deal with biology because in the end we work with cultures of cancer cells. ” she concludes.

7 תגובות

  1. One,

    In my opinion, your difficult and unfounded claims (1) opposition to the employment of women and (2) the empowerment of men require a source/proof.

    post Scriptum.
    In a democratic/scientific discourse there is no place for intimidation of the type "your opinions are dangerous"

  2. Haim, there is opposition to women engaging in the sciences (and other fields). There is empowerment of men in every field (mainly in religion and popular culture. There is a small encouragement in the form of an "award for women in science" to encourage women to go into the field, despite all the nastiness...

    If you are offended by something so insignificant, it is very dangerous in my opinion.

  3. Yehuda: You can't direct the gold particles, but you can decide where you shine the laser. You spread the particles in the blood and sometime they will pass by the tumor. How do you focus a laser on the tumor with such precision, I don't know, this is a problem that already exists in cancer treatment: to treat tumors inside the body with radiation, you need to plan well the radiation mechanism, the location of the radiation sources and the duration.

  4. What is this racist award?
    If there was a prize pre-designated for men only, all the "feminists" would be on the back foot

  5. my father
    There are two women in the picture and you are talking about four names? Gili, Efrat, Asnet and Ruth.
    Apparently suitable for another picture
    good week
    Yehuda

  6. The important question for which there is no answer in the article is:-
    How does the gold particle know how to find the cancer cell and stick to it?
    good week
    Sabdarmish Yehuda

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