resistant bacteria

Bacterial resistance to antibiotics. Prof. Balaban's laboratory at the Hebrew University

Bacteria survive antibiotics in two different 'off modes' – each requiring different treatment

Science Advances presented a distinction between regulated and protected growth arrest and disordered and unstable arrest, with a weak point in the cell envelope that may allow for targeted treatment strategies.
The deadly plague of the "Black Death" in Naples, 1656. Engraving by Miko Spadaro, an eyewitness to the plague. Illustration: depositphotos.com

Israeli researchers have developed a 100% effective mRNA vaccine against antibiotic-resistant bacteria

Researchers from Tel Aviv University and the Institute for Biological Research have developed an innovative vaccine against one of the deadliest bacteria in history – Yersinia pestis, which caused the Black Death in the Middle Ages.
Corals in the Red Sea. Illustration: depositphotos.com

Gifts from the Sea: Molecules from the Coral Sea Could Change the Way We Fight Resistant Bacteria

Researchers at Ben-Gurion University have discovered natural molecules produced by bacteria living on corals in Eilat that reduce the violence of pathogenic bacteria and increase the effectiveness of antibiotics – without the need to kill the bacteria.
Schematic description of one of the approaches in the NanoBiCAR project: Nanoparticles, (1) carrying mRNA molecules that encode a genetically modified protein that activates the immune system, are introduced into the system and taken up by white blood cells formed in the bone marrow (2). These cells produce the protein from the mRNA molecules and secrete it (3). The secreted protein has a dual binding ability: on the one hand, it binds the cells infected with the tuberculosis bacterium (4) or the bacterium itself (5), and on the other hand, it binds killer white blood cells from the immune system (6). The dual binding activates inflammatory and immune processes (6) and ultimately leads to the killing of the cells infected with the bacterium or the elimination of the bacterium itself (7).

mRNA – from vaccines to the fight against tuberculosis

Researchers from the Technion's Faculty of Biology will develop a new approach to combat infectious diseases as part of the European consortium NanoBiCar. This is the first attempt to use mRNA molecules for tuberculosis and other bacterial diseases in light of the difficult problem of bacterial resistance.
Antibiotic resistant bacteria. Illustration: depositphotos.com

An innovative approach to dealing with antibiotic-resistant bacteria

Teeth Whitening. Illustration: depositphotos.com

Adding a molecule synthesized from broccoli to the toothpaste will help prevent bacteria

An international group of scientists, including researchers from Ben Gurion University, suggest adding a natural molecule that will significantly reduce biological infections in the oral cavity.