enzymes

A common ancestral cell that diverges into two lineages of bacteria and archaea in a hydrothermal environment

All known life shares a single origin – but the independent cell may have been born twice

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Reconstruction of about 420 metabolic reactions suggests that the common ancestor of bacteria and archaea still relied on metals in its environment. According to the researchers, the two lineages separately evolved the enzymes that allowed them to exist as independent cells
Artificial intelligence translates protein sequences into natural language descriptions

Artificial intelligence translates protein sequences into natural language descriptions

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The BetaDescribe system, developed by researchers from the Technion and Tel Aviv University, takes a sequence of amino acids and produces a verbal description of the protein's function, chemical activity, and possible binding sites. The researchers hope the system will help choose
The difference between DNA and RNA. Illustration: depositphotos.com

Where did RNA come from? Scientists uncover important chemical clue

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Scientists at the Scripps Research Institute have uncovered new chemical evidence that could explain why the sugar ribose was chosen by nature as a key component in the construction of RNA. The findings strengthen the hypothesis that ribose had a chemical advantage
Agricultural pest control. Illustration: depositphotos.com

Innovative Israeli development for breaking down toxic pesticides: environmentally friendly and safe to use

Researchers from Tel Aviv University, Migal Research Institute and Tel Hai College have developed a biochemical process that combines enzymes and natural bacteria to break down the toxic pesticide paraoxon into harmless substances.
The list of crystals in the zebrafish: in the gill covers (top row) - long and narrow crystals, in the eye of the fish (middle row) shorter crystals, and in the skin (bottom row) - the shortest

The animals' secret recipe book for creating colorful and versatile crystals has been revealed

In the new study, scientists reprogrammed Nicotiana benthamiana plants to produce a wide variety of beneficial sugars found in breast milk, called breast milk oligosaccharides. Credit: Colin Barnum

GM plants produce breast milk sugars that may lead to healthier infant formula

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Today, it is possible to produce a small number of breast milk oligosaccharides with the help of transgenic E. coli bacteria. However, isolating the beneficial molecules from other toxic products is an expensive process, and only a limited number of
Anabina under the microscope. The blue bacteria inspired the research

Bacteria against mutants

Weizmann Institute of Science scientists made bacterial cells mimic processes characteristic of multicellular organisms, and discovered a possible defense mechanism against cancer
fertilizer. Illustration: depositphotos.com

Develops catalysts for clean energy production

Dr. Ariel Friedman, develops solutions in the field of electrochemistry that will lead to green and cheap energy
The enzymes of the start-up company break down the polyethylene terephthalate plastic into its monomers: terephthalic acid as well as ethylene glycol, which themselves can be used directly in existing plants to re-produce the polymer

Plastic recycling with the help of enzymes

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The French biotech start-up company called 'Carbios' succeeded in developing an enzymatic process to recycle the plastic polyethylene terephthalate (Polyethylene terephthalate) back to its component monomers, from which the finished polymer can be produced again
biological enzymes. Illustration: shutterstock

Biological enzymes as a source of hydrogen

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The enzyme aminoacyl synthetase (in green) recognizes a tRNA molecule (brown) and attaches an amino acid to it. Correct identification of the molecule is made according to the areas shown here in red. The Technion researchers discovered that the enzyme also knows how to recognize another type of RNA molecule (mRNA). Moreover, the correct recognition of the mRNA depends on regions that are very similar to the recognition regions of tRNA (marked here in red). Credit: Prof. Yoav Araba, Technion

Researchers have discovered a sophisticated self-regulating mechanism that optimizes the process of building proteins in the body

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This protein-DNA system was assembled by a three-armed DNA triangle of complementary strands forming tetrahedral cages consisting of six sides of DNA and a trimeric protein [Courtesy: Nicholas Stephanopoulos]

Building blocks of DNA and proteins form cage structures

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Dr. Maria Louisa Romero-Romero and Prof. Dan Toufik. Time travel. Photo: Weizmann Institute spokesperson

Following the first proteins

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Bacteriophages attack bacteria. Illustration: shutterstock

Nobel Prize in Chemistry 2018 to three researchers for harnessing evolution to develop environmentally friendly catalysts, proteins and antibodies

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David Hilton - Emergence presented at the Nano Israel Conference, March 2012. Courtesy of the Nano Israel Conference

Every engineer's nightmare

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Enzyme activity in the cell: the enzymes in red, the final product - in blue (see video below). Source: Weizmann Institute magazine.

The first study on the efficiency of enzymes in living cells reveals a surprising limit on their activity

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Comparison between computer models (in green) and experimental structures (in purple). Accuracy at the single atom level in both the overall structure (left) and the loop segments (right). Source: Weizmann Institute magazine.

A computerized method for the production of artificial proteins

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Brown root mushrooms (Gloeophyllum sepiarium) [Courtesy: Karel Tejkal]

Fungi capable of decomposing wood

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Schematic representation of the passage of light through the detector complex of a photoreceptor and the progress of the light to the effector (courtesy: © TU Graz/IBC).

A biological system with a light switch

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Diagram of 3-GSK enzyme. How do complex molecules like proteins work together? Source: Boghog, Wikimedia.

When proteins manage to surprise

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The structure of the enzyme Diacylglycerol kinase as determined at the particle accelerator at Stanford University. [Courtesy: The Biodesign Institute at Arizona State University]

Scientists have revealed the detailed structure of the enzyme diacylglycerol kinase

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His teeth from the University of Pittsburgh and one of the people in his lab hold the enzyme he discovered

A new halogenation enzyme was discovered

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enzymes. Illustration: shutterstock

A reduced catalyst does the work of a collection of enzymes

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Right: structure of a single ring (A) and structure of a double ring (B), known as hexadecameric catenane. Left: The structure of the hexadecameric catenane can be visualized as two interlocking rings.

An enzyme with an unusual and surprising structure

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The biomass of plants can be converted into clean fuel, but this conversion is not yet carried out on a large scale, partly because of its high cost. Illustration: shutterstock

green fuel

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The signaling pathways that the JNK enzyme is responsible for.

A new target for drug development for Parkinson's disease

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From the right: Dr. Binyamin Boren, Prof. Irit Sagi, Moran Grossman and Dr. Dimitri Tavorovsky. active part

On life and water

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On the left: a natural inhibitor (in red) controls the enzyme (gray) by blocking the zinc pool (in yellow) in the cleft where the active site of the enzyme is located. Right: A novel antibody (in purple) works as efficiently as the natural inhibitor. Illustration: Weizmann Institute

An innovative approach to the treatment of autoimmune diseases prevents disease symptoms in mice

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PylB with methylornithine (3MO) and co-factor S-adenosylmethionine (SAM) Image: Felix Quitterer / TUM

Enzymatic synthesis of pyrrolizine, the rare amino acid

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John Shanklin and Ed Whittle, Brookhaven

Revealing the mechanism of activity of an important enzyme

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"Protein anchoring and their binding within nanopores of regular shape to increase their stability and activity"

A method for increasing the stability of enzymes

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From the right: Dr. Moshe Goldsmith, Prof. Israel Silman, Prof. Dan Toufik, Prof. Yoel Zussman, Moshe Ben-David. (Back): Dr. Chaim Lider and Dr. Yaakov Eshani. Defense formation

The liberation movement

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Zachary Ball, Brian Popp

Synthetic enzymes will be able to recognize proteins

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enzymes. Illustration: Max Planck Institute

An innovative method to improve enzyme activity

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A glacier from Scotland and humans completed the path: a possible route to the Stonehenge altar stone

A new artificial enzyme that is safer for the environment

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A glacier from Scotland and humans completed the path: a possible route to the Stonehenge altar stone

Accelerating the artificial evolution of proteins

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A glacier from Scotland and humans completed the path: a possible route to the Stonehenge altar stone

A modern method for improving the properties of enzymes

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A glacier from Scotland and humans completed the path: a possible route to the Stonehenge altar stone

The structure of an enzyme that neutralizes chemical warfare agents has been determined

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A glacier from Scotland and humans completed the path: a possible route to the Stonehenge altar stone

Synthetic pancreatic enzyme - an enzyme with a sugar antenna

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A glacier from Scotland and humans completed the path: a possible route to the Stonehenge altar stone

Researchers use radiation to control protein activity

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A glacier from Scotland and humans completed the path: a possible route to the Stonehenge altar stone

Highly durable germicidal coating for medical protection

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A glacier from Scotland and humans completed the path: a possible route to the Stonehenge altar stone

Synthetic compounds mimic enzyme activity

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A glacier from Scotland and humans completed the path: a possible route to the Stonehenge altar stone

A "green" solution for producing biofuel: enzymes from plants

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A glacier from Scotland and humans completed the path: a possible route to the Stonehenge altar stone

Enzyme is born

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A glacier from Scotland and humans completed the path: a possible route to the Stonehenge altar stone

Scientists from the Weizmann Institute were at the head of the research to produce an artificial enzyme

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A glacier from Scotland and humans completed the path: a possible route to the Stonehenge altar stone

Man-made enzymes

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