drug development

Alzheimer's. Illustration: depositphotos.com

Women respond differently than men to drug treatment for Alzheimer's

Significant differences were found between the reactions of the two sexes to an innovative drug for brain degenerative diseases such as Alzheimer's disease
The Hebrew University in Jerusalem. Illustration: depositphotos.com

Two researchers at the Hebrew University will receive grants of 2 million euros each from the ERC

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In addition, two outstanding researchers from the Hebrew University of Jerusalem were chosen to join the EMBO young researchers program
Prof. Carmit Levy and Prof. Yaron Carmi

Researchers from Tel Aviv University have discovered a new cancer mechanism, the activation of which eliminates cancerous tumors

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Prof. Carmit Levy: Immunotherapy has revolutionized cancer treatment," explains Prof. Carmi, "but about 50% of patients do not respond to the standard treatment - the PD-L1 protein. We found a new protein Ly6a against which treatment with an antibody
cancer cell Illustration: depositphotos.com

What predicts your cancer type?

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Molecular Systems Biology portal showing eCIS injects AI-predicted toxins. Artist's impression by Dr. Yitzhak Yadgari

Identifying new toxins using machine learning

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New research at the Hebrew University reveals how bacteria use a special mechanism, like a tiny syringe, to inject toxins into other organisms. Using artificial intelligence, the researchers identified over 2,000 possible toxins that may be injected through
The bacterium Pseudomonas Aeruginosa causes sinusitis A Hrefhttps Depositphotoscom illustration Depositphotoscom A

Fighting antibiotic resistance using peptide mixtures

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New research highlights the potential of random mixtures of antimicrobial peptides to significantly reduce the risk of resistance development compared to single peptides. These findings highlight the need for innovative solutions to overcome
A fitness pill. Credit: The Science website via DALEE

New 'workout pill' can cause fitness benefits without exercise

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Researchers report new compounds that appear to be able to mimic the physical drive of exercise—at least in rodent cells. This discovery may lead to a new way to treat muscular dystrophy and other medical conditions in people,
Cut in a fetal body. Courtesy of the researchers

How - and where - does a disease begin?

Researchers discovered which genes are required for each stage of cell differentiation into neural stem cells and neurons, i.e. for brain development, and which of them are involved in diseases of the nervous system
Chemical simulation. The image was prepared as an illustration using the artificial intelligence software DALEE and is not used as a scientific image.

Not only in computers: the "legality" of the Restart also works in chemical simulations

Researchers have discovered that the original way to speed up chemical processes is to reboot
drug development. Illustration: depositphotos.com

New insights into polymorphisms could influence drug development

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Researchers have used a variety of methods in order to reveal the different polymorphs that can be prepared from a common crystalline material and the paths of conversion of one configuration to another depending on the temperature and the method of preparation
Researchers have used a variety of methods in order to reveal the different polymorphs that can be prepared from a common crystalline material and the paths of conversion from one configuration to another depending on the temperature and the method of preparation. [Source: Thomas Rades/University of Copenhagen]

New insights into polymorphisms could influence drug development

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Researchers have used a variety of methods in order to reveal the different polymorphs that can be prepared from a common crystalline material and the paths of conversion of one configuration to another depending on the temperature and the method of preparation
Storage of hazardous materials. Illustration: depositphotos.com

A common detergent is linked to a significant increase in the incidence of Parkinson's disease

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For the past hundred years, the chemical trichloroethylene [TCE] has been used in decaffeinated coffee, metal cleaners, and dry-cleaned clothes. The substance itself is known to be a carcinogen, it is associated with abortions, congenital heart disease
Using artificial intelligence to unravel the mysteries of biology. Illustration: depositphotos.com

The artificial intelligence that deciphered biology

Researchers have developed an algorithm known as ART - Automated Recommendation Tool. Art received an enormous amount of information about the set of proteins in the cell, and as a result he could predict how changes in those proteins would affect the substances
Teva and the Technion announce a collaboration to promote innovative research and development in the fields of cancer and the brain. PR photo

Teva and the Technion announce a collaboration to promote research and development in the fields of cancer and the brain

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New models based on deep learning predict the interactions between atoms in organic molecules. These models will help computational biologists and drug developers understand diseases and treat them more efficiently. Courtesy of University of Florida

Artificial intelligence and quantum mechanics will help discover drugs

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fruit fly. Photo: shutterstock

Animal avatars, or - how a cancer patient got help from 300,000 flies

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A platform for the development of accessible drugs for rare genetic metabolic diseases

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Reciprocal reactions between drugs and the patients' genes may have a negative effect on the effect of the drugs and even endanger the patients' lives. Genetic testing may prevent this and help find an alternative drug. Illustration: National Human Genome Research Institute.

adjust the medicine that suits you best

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Chirality. Illustration: shutterstock

A new method for the accurate identification of chiral molecules

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enzymes. Illustration: shutterstock

A reduced catalyst does the work of a collection of enzymes

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Distribution of drugs in the body using nanoparticles. Image: University of Copenhagen

Medical ethics - are drug studies reliable? / Charles Zaif

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Photo 1: The photography system, the automatic incubator and the robot inside the hood. The source of the image: Dr. Solmsky, Tel Aviv University.

So what do you do there at the university? Chapter 14: Let the Robot Work, on Examining Drug Candidates for Personalized Medicine

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Dr. Daniel Albirt, Kaplan Medical Center

Will AIDS turn from a chronic disease to a fatal disease again??

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pills. From Wikipedia

Compugen expands and accelerates the program to develop antibodies to treat cancer and diseases of the immune system

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A chiral surface for drug synthesis. Image: University of Cambridge

An innovative approach to drug synthesis

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A polymeric nicotine trap consists of a porphyrin derivative (black) in which two amide groups (green) are attached to a zinc atom (purple) located in the center of a ring (blue). The nicotine molecule is colored red. The bottom image is a XNUMXD rendering of the polymer.

Nicotine capture polymers

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AT Professor Charlie Johnson who led the research

Researchers have succeeded in attaching odor receptors to nanotubes

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Pub Skeptics logo

One meeting of skeptics in a pub (video)

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Chemicals in glass bottles. From Wikipedia

10 unsolved riddles in chemistry / Philip Ball

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Julia Kubanek, a professor at the Georgia Institute of Technology, holds samples of tropical algae whose surface chemicals are being studied for their potential against malaria. Image: Gary Meek

Antifungal compound against malaria

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Dr. Kobi Nachmias. The Hebrew University of Jerusalem

A scientist from the Hebrew University has developed a nanotechnological drug that helps heal chronic wounds

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nano crystals

Nanomedicines as nanocrystals

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A normal brain (left) and an Alzheimer's disease brain (right)

Medicine - Alzheimer's: to delay the decline of the screen

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Cleaning unwanted proteins from biological drugs. Photo: Rensselaer Institute of Technology

Using an NMR device to purify proteins

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Dr. Oded Lieberman

Neuroderm takes a step forward in the development of the drug for dermal insertion intended for Parkinson's patients

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A chemical lab the size of a credit card. Photo: Polish Academy of Sciences

A chemical lab the size of a credit card

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Trifluoromethyl is attached to a benzene ring (the hydrogen atoms attached to the ring are not shown)

A novel synthesis method for pharmaceuticals

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Lung on a chip. Image courtesy of Wyss Institute for Biologically Inspired Engineering

Development of a human lung on a chip

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hydrogen sulfide

Poisonous gas saves lives

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Schematic diagram of HIV. From Wikipedia

Determining protein structure will help cure AIDS

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Glazed lysosome bead. Photo by Deborah Rickard, Pratt School of Engineering

A new method for turning proteins into glass

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Is there a cure here? Is there a Star of David here? Is the use free? So it fits!

The understanding agreement: Redhill Biopharma will sell to the Australian Giaconda a drug for Crohn's disease

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An example of polyene - Amphotericin B

A new method for preparing important medicines

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Dr. Oded Lieberman

The start-up Neuroderm has successfully completed an important stage in the first clinical trial of a Parkinson's drug

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"By binding the 'combat head' molecule to the peptoid, we have shown that we can increase the protein's killing potential a thousandfold without requiring an expensive and lengthy optimization process," says Prof. Tom Kodadec

New substances to unload proteins

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Minister of Agriculture Benjamin Ben Eliezer on the right, and the chief scientist at the ministry, Dr. Eli Ofer. Photo: Assaf Shiloh - Israel Sun

The chief scientist's research committee approved projects in the field of life sciences amounting to NIS 120 million 

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Artist's impression of an aquareovirus image as computed by Cryo-EM 3-D

An innovative microscope capable of distinguishing individual atoms

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The Koffler particle accelerator. Photo: faithful photographer Michael Jacobson, license - usage

The prize for the encouragement of literary work for scientists in memory of Ofer Lider for the year 2010

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Application logo

Application, Pontifex and Kelal Biotechnology invest 9 million dollars in Abraham Pharmaceuticals

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Symptoms of malaria

Research opens a promising new direction in the treatment of malaria

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