cancer

Mutations. Illustration: depositphotos.com

New 'danger' region discovered in DNA could change what we know about human disease

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A new study has uncovered an important, previously neglected, locus of mutations at the start points of human genes. These regions undergo mutations at a much higher frequency than expected, especially during the earliest stages of embryonic development,
Heart disease and cancer and drug treatments – interactions

Between the heart and cancer: Technion researchers reveal surprising interrelationships between heart disease and cancerous tumors

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Researchers at the Ruth and Baruch Rappaport Faculty of Medicine at the Technion present complex interrelationships between heart disease and cancer, in the hope that the findings will lead to improved treatment of both diseases.
Human lung cancer tissue under the microscope. The helper macrophages (in red) are surrounded by enzymes (in yellow) that activate the stimulating part of the antibodies they develop. This targeted action prevents damage to healthy tissue.

Neutralize the defense, go on the offensive: Smart antibodies to fight cancer

Researchers from the Weizmann Institute of Science have identified immunosuppressive macrophages in tumors and developed smart molecules called MiTEs that target the TREM2 receptor and locally activate IL-2 – with the aim of overcoming resistance to immunotherapy without causing side effects.
The system of restraints and brakes of the immune system. © The Nobel Committee for Physiology or Medicine. Ill. Mattias Karlén

Nobel Prize in Medicine 2025: Discovery of the brakes on the immune system

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From right: Dr. Naama Darzi, Prof. Ayelet Erez, Dr. Natalie Rosenfeld and Dr. Elizaveta Bab-Dinitz. Photo by Weizmann Institute Spokesperson

It's all in the head: Blocking the communication channel between the brain and liver may prevent life-threatening weight loss in cancer patients

Research at the Weizmann Institute of Science demonstrates how communication between the brain and the body's organs plays a critical role in health and disease
Immune system cells attack a cancer cell. Illustration: depositphotos.com

The gene that maximizes sunlight – and may eliminate cancer cells

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Scientists have discovered that SDR42E1, a tiny gene linked to vitamin D absorption, could be the key to treating cancer: When it was turned off in cancer cells, the tumor stopped growing.
The rise of the clones. Illustrator: Itay Chen (student at the Rappaport Faculty of Medicine and professional illustrator of scientific illustrations).

Technion discovery: Genetic "fingerprint" may improve the personalization of immunotherapy treatments

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Researchers at the Rappaport Faculty of Medicine have identified a genetic "fingerprint" that helps predict the effectiveness of these treatments.

A new direction for fighting cancer: making it incriminate itself

Prof. Yardena Samuels' lab at the Weizmann Institute of Science has succeeded in making cancer cells surrender themselves to the immune system. The new approach may offer hope to incurable patients
Overcoming 'blindness' with respect to what is happening deep within the tissue [Photo: Technion Spokesperson]

A new method for non-invasive monitoring of molecular processes deep within tissue

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An innovative approach that simulates the visual system of insects developed at the Technion is expected to impact the monitoring of molecular processes in cancer and other diseases.
Illustration: depositphotos.com

"The Early Warning Signs of Cancer: Epigenetic Discoveries That Inspire Hope"

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New study reveals that cancer risk may be determined before birth, suggesting new directions for diagnosis and treatment
Illustrative epigenetics: depositphotos.com

The Technion will award the Harvey Prize to three groundbreaking researchers in the field of cancer epigenetics

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Prof. Peter Jones, Prof. Steven Bailin and Prof. Andrew Feinberg will receive the Harvey Award in the field of science and technology for their contribution to the diagnosis of diseases and the development of treatments based on the understanding of epigenetic mechanisms
The D'20 peptide inhibits the cancer-causing enzyme MMP7. The image was prepared using DALEE and is not a scientific image

A new stable and selective inhibitor of a cancer-causing enzyme has been revealed in a new study

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Researchers from the Hebrew University, the Weizmann Institute and the University of Tokyo have developed an innovative peptide that suppresses the activity of the MMP7 enzyme associated with cancer progression, with the potential for targeted therapies in aggressive cancers.
Lung cancer. Illustration: depositphotos.com

A new blood test for the early detection of tissue damage caused by cancer treatments

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A method developed at the Hebrew University allows early detection of lung damage among cancer patients receiving antibody-based treatments, using a simple non-invasive blood test
A sample from a tumor of a human patient with the most common lung cancer (adenocarcinoma). The presence of senescent cells expressing the proteins P16 (in red) and PD-L1 (in green) can be detected. The cell nuclei in the sample are marked in blue

to open blockages in the immune system

Comparing the effects of fasting on the health of the digestive system. The image was prepared using DALEE and is not a scientific image

Intermittent fasting: health benefits alongside an increased risk of cancer

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Lung cancer. Illustration: depositphotos.com

Research at the Faculty of Biology at the Technion paves the way for innovative lung cancer treatment

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cancer cell Illustration: depositphotos.com

What predicts your cancer type?

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Photomicrograph of a biopsy from a patient's lungs. Illustration: depositphotos.com

Towards a new generation of treatments for old age diseases

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genetic scan. Illustration: depositphotos.com

Artificial intelligence revealed cancer causes hidden in "junk" DNA

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Research at the University of Sydney suggests that non-coding DNA, which makes up 98% of our genome and was previously considered "junk" – that is, lacking a defined function or redundant, may play a crucial role in cancer diagnosis and treatment.
How a conventional MRI (left) and the home device (right) work

A home MRI scanner may revolutionize medicine

In ten years, it may be possible to find ambulances - or hospitals on wheels - that can reach multi-casualty incidents and provide the doctor in the field with a clear 3D image of each injured person. Doctors will no longer be needed
Right: the opening (red) of the phagophore (green) remains narrow thanks to the coordinated activity of two protein clusters. Left: The opening widened after the scientists reduced the action of the valve that is responsible for closing it

open a little mouth

This is how you maintain a balanced diet of the autophagy organs - the self-eating mechanism in our body cells that removes waste and strengthens our health
The skulls were examined using microscopic analysis and CT scanning. Credit: Tondini, Isidro, Camaros, 2024.

A 4,000-year-old Egyptian skull reveals surgical attempts to treat cancer

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Scientists were amazed by the discovery of cut marks around cancerous tumors on an ancient Egyptian skull, which allowed them to better understand how the ancient Egyptians tried to treat the disease
Anabina under the microscope. The blue bacteria inspired the research

Bacteria against mutants

Weizmann Institute of Science scientists made bacterial cells mimic processes characteristic of multicellular organisms, and discovered a possible defense mechanism against cancer
Cut in a fetal body. Courtesy of the researchers

How - and where - does a disease begin?

Researchers discovered which genes are required for each stage of cell differentiation into neural stem cells and neurons, i.e. for brain development, and which of them are involved in diseases of the nervous system
Dr. Catherine Vandorna. Photo: Nitzan Zohar, Technion spokesperson

This is how the bone marrow reacts to injuries and infections

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Dr. Kathryn Vandorna from the Faculty of Biomedical Engineering at the Technion has developed a new method that allows the monitoring of the formation of immune blood cells in the bone marrow. For this purpose, she used tiny magnetic particles of iron oxide, which
Advances in cancer immunotherapy. The image was produced by DALLE 3 artificial intelligence software and is intended for impressions. It should not be seen as a scientific picture

Technion researchers present a significant improvement in predicting the success of immunotherapy treatments

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The technology developed by Prof. Yuval Shaked's research group was registered as a patent and is now in the process of being commercialized
Tissues removed from mice implanted with lung cancer cells engineered to produce high amounts of PSME4 (left column) or unmodified cancer cells (right column). When the protein is expressed in a high amount, the tumor is larger (top row, the tumor cells are marked in intense and concentrated purple), the number of T cells that can fight the tumor is lower (middle row, in white), and there are more cells that suppress the immune response (bottom row, in green)

The cancer to the basket and eliminated

The cell's garbage disposal system changes in cancer and allows it to escape the immune system
From 0 to 100%: the prediction provided by the model for metasynergy between different drugs

Drug combination in the fight against cancer: an innovative approach that combines biology, chemistry and artificial intelligence

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The research image as published on the cover of Advanced Science magazine

Researchers were able to eliminate most of the myeloma cells in the bone marrow using an RNA-based drug

Thanks to the nanoparticle system they developed - the cancer cell stops dividing and dies
Personalized Medicine Illustrated: depositphotos.com

The discovery that will advance personalized medicine for infectious diseases

This is the first time that researchers succeed in developing personalized tools for infectious diseases, which until now have only been developed for specific diseases such as cancer and Alzheimer's
A new study by Prof. Ofra Bani from the School of Pharmacy at the Hebrew University of Jerusalem and Dr. Sharon Marims - dermatology specialist and senior physician at the dermato-oncology clinic at the Hadassah Medical Center and the Hadassah Cancer Research Institute, published in Science Translational Medicine courtesy of the Hebrew University

A new way to solve side effects of cancer treatment

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Researchers at the Hebrew University and the Hadassah Medical Center have developed an ointment to treat the severe side effects of targeted cancer treatment and significantly improve the quality of life of patients.
The thinness of the cancer. Illustration: depositphotos.com

Why do cancer patients lose weight?

The institute's scientists reveal how cancer leads to fatal emaciation and point the way to treatment
Genetic engineering of T cells - of the immune system. (T Cell-CAR). Illustration: depositphotos.com

Innovative treatment for myeloma and amyloidosis patients

In the clinical trial, T Cell-CAR genetic engineering technology was used to program the patient's white blood cells to attack the cancerous blood tumors
At the beginning of the process, the circular peptides bind to the ubiquitin chain; As a result, the DNA repair mechanism is damaged; And eventually the cancer cells undergo a process of cell death (apoptosis)

Researchers at the Technion discovered unique peptides with anti-cancer potential

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The research was led by researchers from two faculties at the Technion and their colleague from the University of Tokyo
Right: Immune clusters in the liver of a mouse containing ILCs, and within them cancer cells (in red). On the left: immune clusters in the liver of a mouse from which ILCs have been removed, and within them cancer cells. The cancer cells thrive more in the mouse liver which contains ILCs

The immune system gets tired - and the cancer spreads

Pools of immune system cells taken from patients and mice with liver cancer and melanoma, partly composed of tired immune cells
A cancer cell divides. Illustration: depositphotos.com

"Silent" mutations can predict the development of cancer cells

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Researchers from Tel Aviv University have shown that silent mutations, i.e. those that do not change the amino acid sequence of the proteins, are also not innocent
Medical imaging. Photo: depositphotos.com

Development of a radioactive marker to identify small and aggressive cancerous tumors

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A marker developed in a new Israeli study by the University of Bar-in and applied by the start-up company Izotopia will not only determine whether it is a malignant or benign tumor, but also determine to what extent it is
cancer cell Image: Shutterstock

The memories of a cancer cell

A group of scientists at the Weizmann Institute of Science recently investigated what happens to cellular memory in cancer. Their findings illustrate how "memory loss" may affect the course of malignant diseases
pest control Photo: ds 30-Dmitriy Pixabay

Studies show - today's pest control is less dangerous and more economical

When the scientists inhibited the production of the nucleic acid purine in the cancerous tissue (right), more T cells of the immune system penetrated it during the immunotherapy phase, compared to tissue that had not been pretreated with purine inhibitors (left). Photo production: Dr. Raya Elam

Vulnerability is acquired

Weizmann Institute of Science scientists, in collaboration with researchers from the National Cancer Institute and Ben-Gurion University of the Negev, recently found a genetic signature that differentiates between tumors that may respond to immunotherapy and tumors that are resistant to this treatment method. apart from a tool
Imaging of communication between two cells of the immune system - a "combatant" T cell and a "suppressor" myeloid cell. The yellow sparks are meant to illustrate intracellular processes that can be detected using the new method

New technology allows a "peek" into what is happening inside cells

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the lungs. From jumpstory

A new approach to personalized cancer medicine: listening to the internal messages inside the tumor cells

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Bacteria (in green) establish a home in cancer cells and settle comfortably in the cell nucleus area. Source: Weizmann Institute

Cell within a cell: the bacteria that live inside cancerous tumors

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Cancer cell genome. Illustration: shutterstock

Genetic secrets of nearly 2,700 types of cancer have been revealed by an extensive international project

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Prof. Yuval Shaked Photo by Nitzan Zohar, Technion Spokesperson

A Technion researcher presents new ways to curb the development of resistance to cancer treatments

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Stem cells differentiate into neurons and an unsorted stem cell colony. Prof. Yishai Avior, Hebrew University

Fetal stem cells that are used to treat diseases and in research - may contain cancerous mutations

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Early detection of cancer. Illustration: Image by Mohamed Hassan from Pixabay

A nanotechnological biochip for detecting minimal levels of disease markers

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Genomic medicine is changing the face of cancer treatment. Photo: shutterstock

Breakthrough of 2018 according to SCIENCE: Single-cell DNA sequencing

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Nobel Prize for Medicine 2018: Harnessing the immune system to fight cancer

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The top row shows the tumors that developed in the control group mice, and the bottom row - tumors from mice that underwent the brain manipulation. Illustration: Prof. Asia Rolls, Technion

Researchers were able to shrink cancerous tumors in mice by manipulating the reward region of the brain

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