Nano medicine

drug transfer. Illustration: depositphotos.com

Development of the Technion will allow the creation of cells and tissues deep in the body in a non-invasive way with the help of ultrasound

The applicability of the new technology is demonstrated in the contexts of local cell transplantation, drug transport for controlled local release over time and 3D bioprinting. The mechanical properties of the scaffolds can be adjusted according to the target tissue and the rate
The new material 595R developed by the Technion researchers (on the left) alongside the stabilizing materials accepted in the industry. It can be seen that only in 595R the homogeneity of the liquid is maintained over time and the drug particles do not sink. Photo: Sharon Tzur, Technion Spokesperson

Robotic chemistry: a significant step on the way to nanoscale medicine

In the Faculty of Biomedical Engineering at the Technion, an automatic system was developed to create a "nanometric package" for sending drugs to cancer centers in the body
Using nanoparticles to fight cancer. Courtesy of the researchers, University of Tokyo

Using nanoparticles to fight cancer

Researchers have recently succeeded in developing innovative bio-nanoparticles derived from corn designed to tune into and destroy cancer cells, thanks to the body's own immune system
In the diagram: the array of micro-needles is attached to the body, reading and measuring the health parameters from the extracellular fluid below the surface of the skin. The measurement results are sent immediately to the smartphone of the patient and the doctor using cloud and IoT technologies. Pictured: the smart micro-needles are attached to the skin; The microneedle array in the stretch mode

A flexible platform of smart micro-needles for fast, continuous and painless disease diagnosis

The system developed by the Technion researchers is based on smart micro-needles, which are fixed inside a sticker (plaster) that adheres to the skin. The system continuously monitors the patient's medical condition and sends the data to him and his doctor
In the picture are two views (front and back) of lung imaging of a mouse affected by fibrosis (areas painted in gray), before and after receiving nano-treatment directly to the diseased cells.

A nanocarrier for targeting drugs to damaged cells

to the main page. Source: Screenshot from Nagoya University Research YouTube video.

Cancer can be detected in a urine sample

Conceptual illustration of a patch carrying microneedles for the treatment of type 2 diabetes patients. [Courtesy: Chen lab, NIBIB]

Body patch for monitoring sugar levels in diabetics

A nanocapsule of nucleic acids and peptides that releases the medicine inside in response to defined enzymes. (1) in the first step the peptide undergoes cross-linking on the surface of the nanoparticle; (2) In the next step, a defined enzyme recognizes the peptide cross-linking group, (3) and in the last step, the enzyme's release leads to the release of the drug or the nucleic acids that were locked inside the capsule. Courtesy: Joseph Luciani/UConn.

An innovative system for delivering drugs in the body

Dr. Jinao Tang. Source: The University of Hong Kong.

Microscopic robots carry drugs in the bloodstream

Schematic diagram of the system and the DNA molecules conjugated to a synthetic molecule that pulls them through the hole. Right: an example of the optical signal (in two colors) indicating the level of methylation. Courtesy of the Technion.

Unimolecular cancer diagnosis

Diagram from the article, which presents the innovative method developed: "We pack tiny amounts of the anti-cancer drugs inside dedicated nanoparticles that we developed. The uniqueness of these nanometer packages is that they flow in the bloodstream to the tumor and there are swallowed by the cancer cells. To these packages we attach "In advance, artificial DNA sequences are used as barcode readers of the drug's activity in the cancer cells. After 48 hours, a sample (biopsy) is taken from the tumor, and the barcode analysis provides accurate information on the cells that were destroyed (or not) by each drug." Source: Zvi Yaari et al., Theranostic barcoded nanoparticles for personalized cancer medicine, Nature Communications 7, 2016.

Personalized medicine for cancer treatment

peanuts. Source: Stacy Spensley / flickr.

A new anti-allergy bullet

Nanoscale electronic scaffolds into which cardiac cells can be integrated to create cardiac patches in June. The photo shows the nanoelectronic scaffold (in gold) along with recording devices (in purple) and the stimulator (in green) and heart tissue (in red) [Courtesy of Lieber Group/Harvard University]

Development of a June patch for the heart

Nano robots treat a cancer cell. Illustration: shutterstock

Nanomachines for disease diagnosis

Diagnosis of infectious diseases. Illustration: shutterstock

Disease detector

A method for preparing drug carriers and their nanometric structure. The capture and release of the drug depends on the temperature surrounding the carrier system. [Courtesy: Igor Potemkin/Scientific Reports]

Nanocapsules for the precise transport of drugs

Gold nanoparticles in the shape of triangles contained within the innovative detector. [Courtesy: Department of Chemistry and Chemical Biology, School of Science, Indiana University-Purdue University Indianapolis]

Advanced detector for rapid diagnosis of cancer

2. Imaging image. Right: Schematic drawing of the various sensing operations of the platform - touch, heat and volatile particles. Left: photograph and diagram of the chemical resistor; Below: the different parts of the sensor (substrate, electrode and the nanometer sensing layer) before and after a directed scratch. Within 10 minutes the sensor begins to repair itself and return to normal work. Courtesy of Prof. Hosem Haik, Technion

Nanoscale materials will help the chip heal itself following damage

Bandage. Photo: shutterstock

Smart bandages / Peplow soup

Nano robots cruise the bloodstream. Photo: shutterstock

Run the nano-robots / Larry Greenmeyer

human cells. Illustration: shutterstock

Reprogramming cells / Ryan Bradley

Medical sticker. Photo: shutterstock

Wearable detectors for detecting dangerous gases

Hydrophilic carbon aggregate together with polyethylene glycol developed at Rice University has the potential to moderate the overexpression of harmful superoxides through the conversion of active oxygen species that may harm biological functions into neutral oxygen molecules. [Courtesy of Errol Samuel/Rice University]

The great potential of nano-antioxidants

Porous silicon particles are used as a platform to transport anticancer drugs (colored in the diagram in glowing green) and release them in breast cancer tumors. The degradation of silicon in the cancerous tumor environment was studied using innovative imaging methods. The researchers followed the breakdown of the substance in the cancerous tissue and revealed its breakdown mechanism, which allows the release of drugs trapped in the porous medium.

Nanomedicine: Do cancer tumors affect drug release?

Microscope image of gold nanoparticles produced with the help of micro-plasmas on an innovative and extremely sensitive test strip, a strip capable of early detection of heart attacks.

Gold nanoparticles for early detection of heart attacks

The immune system protects the body against viruses and bacteria. Illustration: shutterstock

'Cyber ​​warfare' to aid the immune system against cancer

Image of the nano-syringe developed by BYU researchers for gene therapy.

A new nanodevice for gene therapy

The location of the liver in the human body. Illustration: shutterstock

A revolutionary method for gluing biological tissues

Dr. Leah Geber, Ben-Gurion University

Reverse drive nano motor

Improved chemotherapy method

The Given Imaging endoscopic capsule

Medical technology - robots in pills