Molecular biology of the cell

ribosome. Great protein. Illustration: shutterstock

See transparent

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Chemotherapy. Illustration: shutterstock

LIP-LAP

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A cluster consisting of a "support" protein (grey) and a DNA molecule. The structure of the single helix of DNA (in green), which the model predicted, corresponds to the structure of the helix discovered in the experiment (orange). Source: Weizmann Institute of Science.

positive reinforcements

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Prof. Menachem Rubinstein and research student Efrat Devash. Photo: Weizmann Institute

both

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Bacteriophages attack bacteria. Illustration: shutterstock

Viruses in the service of future medicine

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Prof. Alexander Bershadsky. Cytoskeleton

on the best side

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Melanoma metastases. Left: the RASA2 gene is expressed little or not at all. Life expectancy is lower than normal in about 35 percent of patients. Right: high expression of the RASA2 gene. Life expectancy is higher than usual.

A new gene, a mutation in which leads to the development of cancer in the future, the discovery may allow the development of new anti-cancer treatments

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Proteins are looking for mates. Photo: University of Copenhagen

How do proteins interact with each other?

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The enzyme I-DmoI (purple) conforms precisely to a DNA double helix (yellow and green) [Courtesy of CNIO]

First ever observation of the unwinding of a double-stranded DNA helix

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Normal cells (marked in red) are able to protect cancer cells (in green) from chemotherapy

The resistance of certain cancerous tumors to chemotherapy is due to their connections with healthy body cells

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Image 2: Differentiation process of stem cells into nerve cells. The source of the photo: Sharon*. Human embryonic stem cells grown in cell culture on fibroblasts of human origin. The stem cells are grown on a layer of cells that are used as a feeder layer (on the "feeder layer" left picture). In order to make them differentiate, they are collected and grown as a cluster of cells in suspension (central image), and various substances are added to them that cause them to differentiate into neurons (right image, after 10 weeks of sorting - dyed with a special fluorescent dye green - nerve cells. Blue - the cell nuclei).

How does the process take place in which stem cells acquire their specialization, and become mature cells?

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Melanoma cells. Photo: shutterstock

The characterization of the different types of skin cancer (melanoma) will enable the development of personalized treatment

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From the right: Benny Shapiro, Dr. Nancy Gebert and Prof. Avri Ben-Zev. Standing behind: Anna Shoab and Gal Haz. "The Good Hero". Photo: Weizmann Institute

The double life of the cancer gene

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From the right: Sharina Shetrim, Prof. Rivka Polak, Itai Afudi, Prof. Sanford Sampson, Dr. Yaron Winik, Roi Yitzchak, Prof. Yehiel Zik, Dr. Eitan Elkhanani, Hadas Shatz-Azolai, Dr. Siglit Bora-Chalpon . resistance

Depression, diabetes and everything in between

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Chromosomes in a polyploid stem cell: the cell does not become malignant even though it contains double the amount of most chromosomes

Make a correction

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A new molecular imaging technology that allows them to observe biometals and biomolecules simultaneously in a live mouse. Photo: Ricken Institute in Japan

A new imaging method for observing biomolecules

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From the right: Alina Molchedsky, Gilad Landan, Naomi Goldfinger, Dr. Zohar Mochmal, Prof. Verda Rutter, Netta Mendelson Cohen, Dr. Amos Tanai and Amir Bar. adolescence

Epigenetics: It all depends on education

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