Cancer metastases

Development of melanoma skin cancer. Image: depositphotos.com

Researchers were able to delay by 80% the spread of skin cancer in the body and sending metastases to the brain

Using three-dimensional models of melanoma cancer, researchers were able to decipher the arrival of metastases to the brain
A conceptual illustration of the chess battle between the cancer cells and the anti-cancer drugs. Most cancer deaths are related to the development of drug resistance and the formation of metastases. In both processes, the cancer cells face difficult and new challenges and a strain: finding a bypass for the drug, or a way to adapt to a foreign and hostile tissue. Unfortunately, the cells often manage to overcome these challenges. How does this happen? This is a complex process, and among other things, the cells go through a process of learning, which involves trial and error, while searching among a large number of configurations and internal states. The theory of learning theory constitutes a mental and mathematical framework for understanding these processes. A review of the current literature shows that basic concepts of learning theory provide an explanation for results that do not correspond to the popular concept. Linking the search process to a concrete mathematical model demonstrates its feasibility. (Illustration: Harel Spring)

Lethal learning: a new interpretation of adaptive mechanisms of cancer cells

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Breast cancer cells that express high levels of NUP93 (left) develop fingers that help them move; In contrast, cells without NUP93 are much more stationary (right)

The fight against breast cancer violence

The chemotherapy treatment increases the secretion of LOX from T cells, and as a result the extracellular environment in the lungs changes in a way that encourages the formation of metastases. Photo: Technion spokespeople

Cancer metastases sometimes form following successful chemotherapy treatment

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A lung lobe of a mouse with cancer cell metastases expressing phosphorylated protein, to allow quantification and measurement of the metastases. Credit: Dr. Avi Maimon.

Groundbreaking research: a new protein has been found that significantly inhibits cancer metastasis

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A protective protein, which was generally known to be effective against blood clots, was found to be capable of inhibiting the most violent means of cancer in the human body - metastasis. Prof. Tal Borshtin-Cohen, the leader of the research, believes that the surprising discovery
Cancer metastasis in the brain, originating from lung cancer. Photo: Marvin 101, Wikimedia.

Two genes responsible for the development of brain metastases among lung cancer patients have been identified

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The attached images show how E260 dramatically affects the mitochondria of metastatic cells. From the study.

Researchers have developed a substance that kills cancer metastases without harming normal cells

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Cancerous breast cells (in blue). Source: NIH.

Researchers were able to reduce the risk factors for the spread of cancer metastases after resection of the primary tumor

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The area of ​​operation in the peritoneal membrane of a mouse. The red marking shows the expression of LOX; The green marking shows the hypoxia (lack of oxygen) in the cells. Source: Courtesy of the Technion.

Battle of Lima

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Thyroid cancer cells. Source: NASA / Team Daniela Grimm.

Researchers have developed a new approach to the targeted elimination of aggressive cancer cells

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Cross-sectional image from a confocal microscope: breast cancer cells with high metastatic potential push into a polyacrylamide gel with a stiffness of 2.4 kPa, where this section is at a depth of 10.6 microns below the surface of the gel. In the picture you can see the cell nuclei (red), the actin element in the intracellular skeleton (green) and the connections of the cells to the surface at connection centers (blue).

A fatal warning: researchers have developed a method for estimating the metastatic potential of cancerous tumors

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Thyroid cancer cells. Source: NASA / Team Daniela Grimm.

Carcinogenic groups

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Because before melanoma spreads, it sends out tiny bubbles containing genetic material of the microRNA type, and they create the change in the structure of the dermis - in preparation for the absorption of the cancer cells and the transfer of metastases. Illustration: Tel Aviv University

Researchers from Tel Aviv University discovered the mechanism of the spread of melanoma cancer metastases and found ways to prevent its spread

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divide or conquer

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XNUMXD imaging of colon cancer cells. Illustration: shutterstock

Cancer cells adopt properties of the stem cells of that organ - thus accelerating the spread of metastases

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Cancer cells drift in the bloodstream. Illustration: shutterstock

Glowing proteins that reveal cancer cells in the blood

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From the right: Dr. Rachel Serig, Alina Molchedsky, Dr. Ariel Rinon, Dr. Eldad Tzhor and Prof. Verda Rutter. Rewired

added to his role

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Ovarian tape is bilateral

A new method for early diagnosis of cancer

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Prof. Lawrence Marnett, right, and his colleagues, Prof. Jashim Uddin, right, Prof. David Piston and Brenda Crews, research a compound that causes tumors to glow. Photography: Joe Howell

Luminescent compounds for the detection of cancerous tumors

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Cosmic scene with DNA, stars, solvents and atomic circles in oral flow.

A vaccine for metastatic cancer?

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