Bacterial resistance to antibiotics

Bacterial resistance to antibiotics. Prof. Balaban's laboratory at the Hebrew University

Bacteria survive antibiotics in two different 'off modes' – each requiring different treatment

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Science Advances presented a distinction between regulated and protected growth arrest and disordered and unstable arrest, with a weak point in the cell envelope that may allow for targeted treatment strategies.
The deadly plague of the "Black Death" in Naples, 1656. Engraving by Miko Spadaro, an eyewitness to the plague. Illustration: depositphotos.com

Israeli researchers have developed a 100% effective mRNA vaccine against antibiotic-resistant bacteria

Researchers from Tel Aviv University and the Institute for Biological Research have developed an innovative vaccine against one of the deadliest bacteria in history – Yersinia pestis, which caused the Black Death in the Middle Ages.
Corals in the Red Sea. Illustration: depositphotos.com

Gifts from the Sea: Molecules from the Coral Sea Could Change the Way We Fight Resistant Bacteria

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Researchers at Ben-Gurion University have discovered natural molecules produced by bacteria living on corals in Eilat that reduce the violence of pathogenic bacteria and increase the effectiveness of antibiotics – without the need to kill the bacteria.

New immune mechanism discovered in the cellular trash can

In the laboratory of Prof. Yifat Marbel at the Weizmann Institute of Science, a vast reservoir of antimicrobial substances was discovered that are naturally produced in the body's cells as part of the process of breaking down proteins that have completed their function. The new discovery is
Antibiotic resistant bacteria. Illustration: depositphotos.com

An innovative approach to dealing with antibiotic-resistant bacteria

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Link to a photo of the PL 18 derivative after 72 hours with tubes simulating a catheter - photo credit Yael Schlichter Kadosh

A new type of antibiotic: long pepper

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Bacteria resistant to antibiotics are increasing, while the number of types of antibiotics under development is decreasing. Now, the research group of Prof. Ariel Kushmaro from the Biotechnology Engineering Laboratory at Ben-Gurion University of the Negev and partners from India decided to focus
Molecular Systems Biology portal showing eCIS injects AI-predicted toxins. Artist's impression by Dr. Yitzhak Yadgari

Identifying new toxins using machine learning

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New research at the Hebrew University reveals how bacteria use a special mechanism, like a tiny syringe, to inject toxins into other organisms. Using artificial intelligence, the researchers identified over 2,000 possible toxins that may be injected through
The bacterium Pseudomonas Aeruginosa causes sinusitis A Hrefhttps Depositphotoscom illustration Depositphotoscom A

Fighting antibiotic resistance using peptide mixtures

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New research highlights the potential of random mixtures of antimicrobial peptides to significantly reduce the risk of resistance development compared to single peptides. These findings highlight the need for innovative solutions to overcome
The image illustrates the complex interactions described in your summary, and shows the complex choices that bacteriophages make between aggression and dormancy within their bacterial hosts, which are influenced by environmental cues and the health of the host. This represents the sophisticated mechanisms at work in bacterial and viral interactions as revealed by the study. Credit: The Science website via DALEE

How do viruses decide whether to stay friendly?

This is how the decision-making mechanism of viruses works
A specific and particularly successful phage named PASA16 discovered by the Israeli center treated 16 patients, most of them severe, and it demonstrates the high potential effectiveness of treatment in dealing with challenging and antibiotic-resistant Pseudomonas aeruginosa infections. Photography: Ronen Hazan

Innovative treatment with phages in antibiotic-resistant infections has over 80% success rate in Pseudomonas infections

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A new international study on treatment using the PASA16 phage (a virus that kills only bacteria), showed a success rate of over 80% and gives hope for a beneficial treatment for resistant infections
mRNA. Illustration: depositphotos.com

Scientific breakthrough: for the first time in the world an mRNA vaccine against deadly bacteria

Researchers succeeded for the first time in the world in developing a vaccine against a deadly bacterium, opening the door to mRNA vaccines also against antibiotic-resistant bacteria
The nano 'spikes' formed from a combination of copper with the polysaccharide, cause damage to the bacteria's membrane and thus kill them. From a study by Prof. Ariel Kushmaro Credit: Sharon Amalani, Ben Gurion University

Thorns in the war against bacteria and fungi

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Long and dense spikes formed by a sulfated polysaccharide substance found in red algae were discovered by a research group from Ben-Gurion University of the Negev to have biological activity against bacteria and fungi
Antibiotic combinations. Image: depositphotos.com

Antibiotic combinations - are they effective?

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Technion researchers have developed a technology to measure the long-term effect of "combination therapies"
Bacteriophages attack bacteria. Image: depositphotos.com

An innovative therapeutic approach mobilizes viruses to intercept disease-causing gut bacteria

In a study published today in the scientific journal Cell, Weizmann Institute of Science scientists demonstrated an innovative therapeutic approach that performs "targeted defeat" of unwanted intestinal bacteria using a creative and precise weapon - viruses that attack
Illustration: depositphotos.com

Injection of honey prevents infections in horses

The results of a study conducted at the Veterinary Hospital of the Hebrew University show that the treatment significantly reduced the rate of infections from 32% to 8%. It is possible that the use of honey could reduce or replace the use in the future
Streptococcus bacteria. Illustration: depositphotos.com

Substances that allow the body to eliminate the predatory bacteria completely

Treating the host and not the bacteria is a breakthrough for the development of innovative and effective treatments that do not cause the development of resistance to antibiotics
The process of a bacteriophage taking over the genetic material of a bacterium. Prof. Udi Cameron, Tel Aviv University

A mechanism has been revealed by which "good" viruses eliminate "bad" bacteria and stop their culture

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Researchers from Tel Aviv University have discovered a process in which a "good" virus manages to selectively destroy the DNA of the "bad" bacteria, thus stopping the reproduction of the bacteria. The discovery may help in the development of treatments against bacteria
Colonies of bacteria grow in a petri dish. Photo: depositphotos.com

How can interactions between bacteria predict evolutionary changes in the microbiome?

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In a study published in Nature Communications, Dr. Yonatan Friedman and PhD student Nitai Maroz from the Faculty of Food and Environmental Agriculture at the Hebrew University bring science closer to engineering a unique microbiome for specific needs in humans, animals, plants and the environment
A picture of the tweezers from the study. Courtesy of Ben Gurion University

The advanced generation of antibiotics: molecular tweezers

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A new study published by researchers from Ben-Gurion University of the Negev in collaboration with scientists from the USA and Germany offers a new development to combat antibiotic-resistant bacteria: the use of "molecular tweezers" that damage the biofilm that protects the bacteria
Dr. Livnat Giorno Apriat. Communications credit 4

On evolutionary pathways of enzymes and communication between sophisticated bacterial populations

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Dr. Livnat Apriat-Gourno and her laboratory team at the Miguel Applied Scientific Research Institute, aims to apply the knowledge obtained and improve a variety of enzymes such as those that effectively break down communication molecules between bacteria, as a treatment against disease-causing bacteria
Biofilm with antibiotic-resistant bacteria on it. Image: depositphotos.com

Do not rush the medicine

A new report by the Ministry of Health found that strengthening the regulation and supervision of veterinary preparations is an important way to reduce the use of antibiotics in farm animals, which is one of the main causes of bacterial resistance to antibiotics
Schematic description of the mechanism by which a bacterial biofilm is destroyed by reactive oxygen species

Nanocrystals that eliminate bacterial biofilm

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A team of researchers managed to control the surface texture of nanostructures
Dr. Natalia Freund. Photo: Tel Aviv University Spokesperson

The substitute for antibiotics that the body produces itself

Antibiotics and children. Photo: depositphotos.com

A connection was found between receiving antibiotics early in life and growth retardation in boys

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Prof. Omri Koren from the Faculty of Medicine of Bar-Ilan University in the Galilee, together with researchers from around the world found that children who received antibiotics in the first two weeks of life were less tall compared to their peers. The phenomenon was observed in boys only,
Salmonella bacteria (bright green) inside macrophages (yellow-brown) of a mouse. Dr. Roy Avraham, Weizmann Institute

Salmonella melons

This is how bacteria turn the cells of the immune system into an all-inclusive hotel: bacteria swallowed by macrophages sometimes manage not only to survive but even thrive inside them, as if they were incubators that help spread
Australian tree toad. Photo: depositphotos.com

The biological armor of the Australian toad

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Researchers at the Faculty of Biology at the Technion have deciphered a mechanism that protects the Australian toad from hostile bacteria
Fighting antibiotic-resistant bacteria. Illustration: illustration: depositphotos.com

Omnix Medical has completed raising $10 million for a clinical trial of a drug against resistant bacteria

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Graphene to destroy drug-resistant bacteria. From Scientific Research, Rice University

Graphene to destroy drug-resistant bacteria

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Graphene shell helps particles destroy drug-resistant bacteria in wastewater treated in dedicated facilities
Bacterial resistance to antibiotics. Illustration: shutterstock

Artificial intelligence has discovered a surprising new antibiotic

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Prof. Nathalie Laban. Photo: Hebrew University Spokesperson

The researcher from the Hebrew University who is trying to save antibiotics

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germs. Illustration: shutterstock

MeMed has been recognized as a "technological pioneer" by the World Economic Forum

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Bacterial resistance to antibiotics. Illustration: national review of medicine

The deadly ingredient: bacterial resistance to antibiotics and overcrowding in hospitals

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Synthesis of thio-peptides using a molybdenum catalyst

A breakthrough in the chemical synthesis of antibacterials will serve as another weapon in antibiotic resistance

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Antibiotic resistant bacteria. Illustration: shutterstock

How can you fight bacterial resistance to antibiotics?

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Bacterial resistance to antibiotics. Illustration: national review of medicine

A new method for estimating the effectiveness of "antibiotic cocktails"

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Antibiotic resistant bacteria. Illustration: shutterstock

Antibiotic resistant genes

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Deadly bacteria: colonies of Bacillus anthracis grown on an agar medium in the laboratory. Source: US Army Medical Research Institute of Infectious Diseases.

Improving the monitoring of the three-dimensional structure of bacterial colonies to prevent their resistance to antibiotics

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Thief Ant, CC 4.0

Antibiotic development inspired by the ants

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The streptococcus bacteria attacks the throat tissue. Photo: Shutterstock

Improving the effectiveness of antibiotic drugs will allow them to better deal with bacteria

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Calcium carbonate walls that protect a bacterial colony. Illustration: Weizmann Institute

Break down walls - and heal

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A display illustrating the danger to animals in the sea as a result of the plastic waste that fills the sea, at the Natural History Museum of Berlin. Photo: Avi Blizovsky

How do the bacteria that eat plastic work? A chemist explains

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The Research Regulation Council: plans to ban experiments on antibiotic-resistant bacteria

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Cross section of the large subunit of the bacterial ribosome. In yellow - the exit tunnel of the proteins from the ribosome. In red - the binding pocket of erythromycin at the entrance to the tunnel. Bottom right (marked in light blue) – the ribosomal protein L22. In structural and chemical terms, the protein is distant from the binding pocket of the antibiotic. Source: Weizmann Institute magazine.

Researchers have discovered how a mutation in a ribosomal protein helps bacteria develop resistance to antibiotics

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Sandstorm in Iraq, 2005. Photo: Corporal Alicia M. Garcia, US Marine Corps.

The genetics of dust storms

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Photo: Technion spokespeople.

Researchers from the Technion have developed a system that allows rapid personalization of the antibiotic medication for the patient

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Bacteriophage simulation. Source: naturalismus.

Researchers have developed a technology that enables the "reprogramming" of bacteria

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Dr. Zvi Chioka. Source: Courtesy of the Hebrew University.

Researchers have developed antibiotics against antibiotic-resistant bacteria

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Staphylococcus aureus bacteria. Source: NIAID.

The poisoned arrow of the golden bacterium

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antibiotic drugs. Illustration: pixabay.com.

"Antibiotics are like an atom bomb on the microbiome"

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From the right: Maya Shamir, Daniel Dar and Prof. Rotem Sorek. short coils

Someone turned off the switch

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