Ayelet Erez

When the scientists inhibited the production of the nucleic acid purine in the cancerous tissue (right), more T cells of the immune system penetrated it during the immunotherapy phase, compared to tissue that had not been pretreated with purine inhibitors (left). Photo production: Dr. Raya Elam

Vulnerability is acquired

Weizmann Institute of Science scientists, in collaboration with researchers from the National Cancer Institute and Ben-Gurion University of the Negev, recently found a genetic signature that differentiates between tumors that may respond to immunotherapy and tumors that are resistant to this treatment method. apart from a tool
A section of a mouse brain showing the expression of the ASL enzyme (in purple) in the brainstem region called the locus coeruleus. The laboratory of Prof. Ayelet Erez, Weizmann Institute

On the way to the brain, we stop at the liver

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Mouse embryonic stem cells were observed using a spinning disk confocal microscope. The levels of the protein that prevents stem cells from differentiating (green) decrease in the presence of high levels of another protein (purple) that causes mitochondria to elongate

The elongation of mitochondria in embryonic stem cells affects the process of differentiation into the various body tissues

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Dr. Ayelet Erez. Photo: Weizmann Institute of Science Spokesperson

A new option for cancer detection: detection of disturbance in nitrogen metabolism

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The intestinal lining near a cancerous tumor. The enzyme ASL (reddish brown), essential for the production of nitric oxide, accumulated in large quantities in the mucosal cells, probably in an attempt to reduce intestinal inflammation, which often precedes colon cancer. Photo: Ayelet Erez, Weizmann Institute

Helping the body to help itself: how to relieve Crohn's and colitis?

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A genetic disease caused by a mutation in a single gene. Illustration: Weizmann Institute

How a single gene that causes a rare disease helps in understanding complex diseases like cancer

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Dr. Chai Dvir. Photo: Technion

"It's a good idea to prepare a plan to return to Israel already when you leave for a doctorate"

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Dr. Ayelet Erez. Photo: Weizmann Institute

double track

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