Tune Therapeutics

An illustration of epigenome editing: A CRISPR-guided system binds to a specific region of DNA and changes chemical marks that affect gene activity, without cutting the genetic sequence itself.

The Next Generation of CRISPR: Epigenome Editing Moves to Human Trials

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New systems use CRISPR's navigational capabilities to silence or activate genes without cutting DNA. First clinical trials in FSHD and hepatitis B are testing whether epigenetic modification can be targeted, safe
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