Regenerative medicine

A Mexican axolotl in the regeneration lab of biologist Josh Curry of Wake Forest University. Credit: Wake Forest University

New study points to genetic pathway for organ regrowth

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Identifying genes shared by different animals opens the door to developing gene therapy treatments that will enable limb reconstruction in humans in the future.
Nerve damage. Illustration: depositphotos.com

From the nose to the spinal cord: Norexone sends tiny “messengers” to repair damaged nerves

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Exosomes loaded with siRNA against PTEN, developed at the Technion and Tel Aviv University, are designed to reduce inflammation and encourage regeneration in the central nervous system – an area that is also relevant to myelin damage such as in multiple sclerosis.
Prof. Tal Dvir from the Sagol Center for Regenerative Biotechnology, head of the Nanotechnology Center at Tel Aviv University and chief scientist of the biotech company Trisself. Photo: Tel Aviv University Spokesperson

Tel Aviv University researchers have developed a human spinal cord implant that allows paralyzed people to regain movement

A team led by Prof. Tal Dvir has succeeded in growing a customized spinal cord transplant from the patient's own cells. After success in animals, the Ministry of Health has approved the first human trial in Israel.
Microscopic image of a fetal kidney grown in the laboratory. Photo: Sheba Spokesperson

For the first time in the world: Sheba and Tel Aviv University researchers grew fetal kidney components from stem cells

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The kidney grew and developed over many months and underwent processes similar to those in pregnancy | The organoid allows for the development of regenerative medicine treatments, testing drug toxicity during pregnancy on fetal kidneys, and shedding light on birth defects
Activation of aldh1a2 may reactivate regeneration in mice. Credit: Wei Wang Lab at the National Institute of Biological Sciences, Beijing

Activating a silent gene revives tissue regeneration in mice

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New research reveals that restoring the activity of an ancient gene allows mice to regenerate damaged ear tissue – a finding that could pave the way for breakthroughs in regenerative medicine
chromatin structure. Illustration: depositphotos.com

How proteins and DNA shape cell identity

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New research reveals a fascinating mechanism of "guided search," in which DNA and chromatin structure act as a "road map," directing proteins to specific genetic targets. The mechanism provides new insights into the acquisition of cellular identity that may promote
Cut in a fetal body. Courtesy of the researchers

How - and where - does a disease begin?

Researchers discovered which genes are required for each stage of cell differentiation into neural stem cells and neurons, i.e. for brain development, and which of them are involved in diseases of the nervous system
pluripotent stem cells. Illustration: depositphotos.com

Stem cells used as a basis for innovative medicine may contain cancerous mutations

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A study by researchers at the Hebrew University found that in mature cells derived from stem cells, which are used in the field of regenerative medicine that focuses on renewing living tissues and creating organs for transplantation, cancerous mutations may appear
Embryonic stem cells. Illustration: depositphotos.com

Going deeper into the roots of the diseases

Researchers have built cellular models of genetic diseases such as fragile X syndrome and found the mechanism that causes them
A "ghost" heart is a pig heart that has been prepared so that it can be transplanted into humans. Provided by Doris Taylor

"Ghost" hearts from a pig and the patient's stem cells will replace the need for heart donations

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Today, patients needing a heart transplant have to join a waiting list, and hearts become available when someone else dies. Because there are not enough hearts, only critically ill patients are put on the waiting list
Cells. Illustration: depositphotos.com

Start with one cell

The long and winding road to doubling the amount of biological material available for research
Using stem cells to grow organs for transplantation. Illustration: shutterstock

"By regulating and controlling processes in the cell, it will be possible to treat diseases and injuries that are difficult to treat in conventional ways."

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The structure of the liver. Figure: Wikipedia

Laboratory-engineered human livers, made in Israel... almost

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the lungs

artificial lung

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Images: Carlson Lab/Brown University and Morgan Lab/Brown University

Grow an egg in a petri dish

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Spotted salamander. From Wikipedia

Dr. Anthony Atala's laboratory for growing organs from patients' cells: the solution to the shortage of organs for transplantation

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Tensegrity built with rods and strips

Nanodevices that move and change their shape on demand

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LCD monitors no longer die in vain

Waste from LCD TVs to prevent bacterial infections

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Biopolis center where ESI operates

BioTime announces the completion of the acquisition of ES Cell International Pte

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Prof. Samdar Cohen, Ben-Gurion University

For the first time, the Rapaport Award for excellence in the medical field is awarded

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Cosmic scene with DNA, stars, solvents and atomic circles in oral flow.

The Broken Hearts Facility Club

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Cosmic scene with DNA, stars, solvents and atomic circles in oral flow.

The European Union finances a project to improve the quality of life of people suffering from back pain, with the participation of Technion researchers

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Cosmic scene with DNA, stars, solvents and atomic circles in oral flow.

Doctoral student on the road - part six - Roy's lecture

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Cosmic scene with DNA, stars, solvents and atomic circles in oral flow.

A new way to repair spinal cord injuries - a "liquid" bridge may help severed nerve cells to grow

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Cosmic scene with DNA, stars, solvents and atomic circles in oral flow.

A three-dimensional tissue emerges from stem cells and a scaffold

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