gene editing

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Edit, domesticate, grow: CRISPR brings an unknown relative of the tomato to the field

Cold Spring Harbor Laboratory researchers have edited genes in Golden Berries to produce plants that are about 35% shorter and easier to plant and harvest, and plan to further improve traits such as fruit size and disease resistance.
Human cells that have undergone gene editing using a novel retron-based gene editing technology. The orange dots indicate successful gene edits. The green dots show a fluorescent protein tag on the surface of mitochondria. Credit: Yu-Cheon Chang / The University of Texas at Austin.

New retron-based DNA editing method to replace CRISPR offers hope for broad treatment of complex genetic diseases

Researchers at the University of Texas at Austin have developed a gene editing technique that can replace damaged DNA segments in their entirety, simultaneously correct a variety of rare mutations, and achieve an efficiency of about 30% of target cells – with initial applications
Transferring medical information via chatbot. Illustration:

Researchers call for adopting a collaborative model in scientific communication that combines values, open discourse, and recognition of uncertainty

Researchers call for adopting a collaborative model in scientific communication that combines values, open discourse, and recognition of uncertainty
The UC Berkeley research team used CRISPR/Cas9 to increase gene expression in rice by modifying its upstream regulatory DNA. While other studies have used this technology to inactivate or decrease gene expression, this study is the first to use gene editing without bias to increase gene expression and subsequent photosynthetic activity. Credit: RIPE Project.

A research team uses CRISPR/Cas9 to change photosynthesis properties of agricultural crops

While other studies have used CRISPR/Cas9 gene editing to disable or decrease gene expression, the new study published in Science Advances used unbiased gene editing for the first time to increase gene expression and subsequent photosynthetic activity.
Mice. Illustration: depositphotos.com

Mice with two fathers: Scientists create eggs from male cells

The researchers behind the new study were able to create baby mice with genetic material from two males without any genetic changes. They achieved this by using stem cells to create primordial germ cells (PGCs),
By reprogramming the DNA of harmful microorganisms, such as the E. coli bacteria pictured, biologists turn them into drugs that save patients' lives. Source: NIAID.

Reprogramming bacteria saves life