Amyloid beta

Hippocampal dentate gyrus in HSHA mice, showing significant activation of astrocytes (GFAP: white) and oxidative stress (8OHdG: green) surrounding brain capillaries (laminin-a4: reddish). Nuclei are stained with DAPI (blue). Credit: John Charles Lewis Mammo, Lam V et al., 2021, PLOS Biology. Credit: John Charles Louis Mamo, Lam V et al., 2021, PLOS Biology

Protein from the liver may cause Alzheimer's disease in the brain

Summary: Amyloid-beta proteins formed in the liver are carried in the bloodstream by lipoproteins to the brain. This causes neurodegradation, brain degeneration and inflammation, common features of Alzheimer's disease.