Leukemia

Silencing the IPO11 gene inhibits acute leukemia cells in culture and in mice

Silencing the IPO11 gene inhibits acute leukemia cells in culture and in mice

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Hadassah researchers identified that the gene, which is involved in transporting proteins into the cell nucleus, is essential for the growth and function of acute myeloid leukemia cells. Silencing it also affected leukemic stem cells taken from patients, but the path to developing a cure
The team observed the emergence of 3D embryo-like structures under a microscope in the lab. After about two weeks of development, they began to produce blood (shown here in red) — similar to the development process in human embryos. Credit: Jitesh Neupane, University of Cambridge

Human embryo model grown in lab conditions produces blood cells

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Cambridge researchers have created “hematoids,” self-organizing structures from stem cells that mimic early stages of development, including blood stem cells and beating heart cells.
An Egyptian mummy excavated from the tombs of the pharaohs. Illustration: depositphotos.com

The mold that caused the curse of the pharaohs becomes a weapon against leukemia

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Scientists have managed to engineer compounds from the mold Aspergillus flavus that defeat leukemia cells – signaling hope for new drugs from nature
Leukemia. Illustration: depositphotos.com

The blood test that will identify the risk of leukemia – and may replace bone marrow aspiration

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Just days after their laboratories were damaged in an Iranian attack, Prof. Liran Shlush and Prof. Amos Tanai publish groundbreaking findings that are expected to advance the field of blood cell medicine.
Illustration: depositphotos.com

"The Early Warning Signs of Cancer: Epigenetic Discoveries That Inspire Hope"

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New study reveals that cancer risk may be determined before birth, suggesting new directions for diagnosis and treatment
leukemic cells. Evolve from "cancer stem cells". Photo: Mary Ann Thompson / Wikimedia.

Is it possible to identify, already in the initial diagnosis, signs that the cancer is going to return?

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Leukemia: shutterstock illustration

A "horror balance" between a normal gene and its mutation, is responsible for some cases of leukemia

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The experimental system: two nostrils from which exit ultrasonic beams of excited helium atoms (in blue) and of argon atoms or hydrogen molecules (in red). The blue beam passes through a magnetic device (in yellow) which causes it to bend, and merges with the red beam - then the argon atoms or hydrogen molecules undergo ionization, and enter the detector. The picture above shows a cross-section of the magnetic device

expression and control

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