gene expression

First genetic atlas of the human liver reveals eight areas of activity and vulnerability to fatty liver

Scientists from the Weizmann Institute, Sheba, and Mayo Clinic have mapped the healthy human liver for the first time at a resolution of 2 microns, discovering that the division of functions in it is more complex than in other mammals, explaining why certain areas are sensitive to
Liver infected with hepatitis. Illustration: depositphotos.com

When the virus leaves a mark: Epigenetic “stamp” after hepatitis C cure may explain ongoing risk of liver cancer

Research led by Prof. Meital Gal-Tanaami of Bar-Ilan University and supported by the Israel Science Foundation is examining how a virus that remains in the cytoplasm manages to change genetic control in the nucleus, and is attempting to map points of intervention to reduce cancer risk as well.
Chromosomes A Hrefhttps Depositphotoscom Illustration Depositphotoscom A

The silent competition within us: How our organs choose between mom's and dad's genes

Research conducted by the MRC Medical Sciences Laboratory reveals that cells in different organs selectively express maternal or paternal X chromosomes. This variability, which has been shown in both human data and
The UC Berkeley research team used CRISPR/Cas9 to increase gene expression in rice by modifying its upstream regulatory DNA. While other studies have used this technology to inactivate or decrease gene expression, this study is the first to use gene editing without bias to increase gene expression and subsequent photosynthetic activity. Credit: RIPE Project.

A research team uses CRISPR/Cas9 to change photosynthesis properties of agricultural crops

While other studies have used CRISPR/Cas9 gene editing to disable or decrease gene expression, the new study published in Science Advances used unbiased gene editing for the first time to increase gene expression and subsequent photosynthetic activity.
Embryonic stem cells. Illustration: depositphotos.com

Going deeper into the roots of the diseases

Researchers have built cellular models of genetic diseases such as fragile X syndrome and found the mechanism that causes them
Different species of foraminifera. Illustration: depositphotos.com

The marine microorganisms that indicate climate change

What makes foraminifera species sensitive to heat?
The cellular signaling system. Illustration: depositphotos.com

A team of Israeli researchers has mapped the way in which DNA is labeled in all the cells of the human body

The database also includes thousands of new biomarkers that will make it possible to detect cell death and to diagnose in the early stages a variety of diseases in the most important systems of the human body, through a blood test
Human Genome. Image: depositphotos.com

A new comprehensive map links every human gene to its function

The study of genetics has progressed rapidly in recent decades. For example, just a few months ago, the first complete, gap-free sequencing of the human genome was announced. Now the researchers have gone ahead again and created the comprehensive functional map
How the body packs 2 meters of DNA into a tiny cell nucleus. Courtesy of Tel Aviv University

How does the human body pack 2 meters of DNA into a tiny nucleus that is only a few thousandths of a millimeter in size

Since the genes are found along the length of the DNA, then the staggered way in which the DNA is arranged inside the nucleus separates the genes according to the content of their building blocks and thus the DNA is actually packed inside the tiny nucleus
Breast cancer cells that express high levels of NUP93 (left) develop fingers that help them move; In contrast, cells without NUP93 are much more stationary (right)

The fight against breast cancer violence

Neurons in XNUMXD. Illustration: shutterstock

The neurons in the brain are much more diverse than we thought

identical twins. Photo: shutterstock

What makes some identical twins look different from each other?

From the right: Dr. Amnon Buxboim, Dr. Shirley Dauba, Prof. Roi Bar-Ziv and Dan Bracha

Dense in the genome

Light switches the action of the transcription factor AP-1 (blue-green) in living cells through the inhibitor (red-yellow) modified by a light-sensitive chemical adapter. Credit: Albert Ludwig University Freiburg

A new method for controlling proteins

Christmas Island crabs on the move

How do lazy crabs turn into marathon runners overnight?

Symptoms of malaria

Research opens a promising new direction in the treatment of malaria

A glacier from Scotland and humans completed the path: a possible route to the Stonehenge altar stone

A method for identifying a stem cell with unlimited differentiation capacity

A glacier from Scotland and humans completed the path: a possible route to the Stonehenge altar stone

How do embryonic stem cells differentiate?