In addition, two outstanding researchers from the Hebrew University of Jerusalem were chosen to join the EMBO young researchers program
The European Research Council of the European Union (ERC) announced today (Tuesday) its support for a number of Israeli research proposals, 2 of which are led by Hebrew University researchers. The two Hebrew University researchers who will receive the grant this year will join dozens of other university researchers who received the grant in previous years.
The recipients of the grants from the Hebrew University are:
Prof. Dina Schneidman from the School of Engineering and Computer Science won a grant of 2 million euros for a research proposal in the field of deep learning for the structure-based discovery of receptors of the adaptive immune system:
The human immune system relies on a huge variety of receptors in B and T cells, called adaptive receptors of the immune system, to recognize and fight a wide variety of infections. Modern technologies allow us to sequence these receptors from humans, but deciphering this data for the purpose of understanding infections and pathogens we have been exposed to in the past or to guide medical decisions remains a major challenge.
While traditional experimental methods for obtaining this information are expensive and slow, breakthroughs in the field of artificial intelligence, and especially deep learning, have changed our ability to predict protein structures and this year's Nobel Prize in Chemistry was awarded. However, these methods often rely on information derived from evolutionary data, which is not available for these rapidly evolving receptors. The group led by Prof. Schneidman is developing innovative methods in geometric deep learning to deal with this limitation.
This project focuses on mapping pathogenic proteins that the immune system receptors recognize using precise three-dimensional structures. In addition, he will be involved in the development of advanced tools, based on deep learning, to design receptors that can be used as innovative drugs.
These tools are expected to change the way immune responses are studied, to accelerate the development of vaccines and medical treatments, and to support advanced research in the fields of cancer and autoimmune diseases.
Analysis of thousands of classical music works to examine the processes of change in musical styles
Prof. Yoel Greenberg from the Department of Musicology won a grant of 2 million euros for the research proposal "Towards a Diachronic Musical Theory":
This research aims to revolutionize the field of music theory by focusing on the processes of change in musical styles over time instead of focusing on the definitions of rigid time frames. This groundbreaking approach will involve the analysis of thousands of musical works composed between 1680 and 1829, and examine how stylistic changes occurred. Through the study of trends in musical forms, sentence structure, cadences, and regular musical patterns, the research will reveal the forces driving musical development, as well as offer a new perspective for music theoretical research. The project will not only enrich our understanding of historical musical styles, but also provide a flexible framework for re-examining musical theories and their methods in the digital age.
Since 2007, grants from the European Research Council of the European Union have been given to independent researchers who have stood out in their achievements. The winners are selected from among thousands through research proposals submitted from universities all over Europe. The proposals presented are from groundbreaking researchers who have demonstrated a real potential to lead an independent career in the field of research later on. The two university researchers who will receive the grant this year will join dozens of other university researchers who received the grant in previous years.
Two outstanding researchers from the Hebrew University of Jerusalem were chosen to join the EMBO program for young researchers
Two outstanding researchers from the Hebrew University of Jerusalem were chosen to join the EMBO Young Researchers Program. The researchers from the Hebrew University are among the 27 newest members of the EMBO network, a prestigious European program for heads of outstanding research groups at the beginning of their career in the life sciences that promotes scientific excellence and interdisciplinary collaborations. As part of the program, they will receive a grant of 15,000 euros, access to central facilities at the EMBL research institute in Heidelberg (Germany), training in laboratory management and responsible research methods, as well as professional guidance by EMBO members. The program also provides opportunities to submit applications for additional funding as well as organizing or participating in international conferences.
The biology of aging
Dr. Itamar Harel, from the Alexander Silverman Institute of Life Sciences: Dr. Harel is conducting ground-breaking research on the biology of aging using the African turquoise killifish as a research model. This short-lived vertebrate, which shares key genetic and physiological features with humans, enables effective research into aging processes and age-related diseases such as Parkinson's and Alzheimer's Dr. Harel's work identified proteins that suffer from failures that occur with age, which lead to cell disorders. body, and also revealed species-unique mechanisms, including how the germline affects male longevity and enhances DNA repair in females. These findings provide novel insights into the molecular mechanisms that drive aging and suggest possible ways to slow aging and fight age-related diseases.
"I am excited to join the EMBO Young Investigator Program as it offers my students a wonderful platform to collaborate with outstanding scientists from diverse fields. Participating in this vibrant community is an incredible opportunity to accelerate the impact of our work and inspire the next generation of researchers."
Cooperation between the Rekh Institute of Physics and the Faculty of Medicine
Dr. Mor Nitzan from the School of Engineering and Computer Science, Rakah Institute of Physics and the Faculty of Medicine: Dr. Nitzan leads research dealing with the representation, inference and design of multicellular systems. She develops mathematical models and computational frameworks with the aim of better understanding how cells encode many layers of spatial and temporal information, and how this information can be efficiently decoded from large and complex biological data. The research group Shela aims to reveal principles of organization that underlie information processing, calculation, division of labor and self-organization of buildings multicellular like tissues, and investigate how interactions between cells can be influenced to improve tissue structure and function.
More of the topic in Hayadan:
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