August 26, 2026

A lipid nanoparticle delivers an anti-alpha-synuclein antibody into a neuron in a Parkinson's model

"Trojan Horse" into the Cell: Nanoparticles Introduced Antibodies into the Brain in a Parkinson's Model

Researchers from Tel Aviv University, the Technion, and Cornell wrapped antibodies in temporary chemical “camouflage” and packaged them in lipid nanoparticles. In a preclinical model, the antibodies were able to reach nerve cells and reduce alpha-synuclein aggregates—but
Ionized hydrogen map of J0148-4214 showing the locations of the three black holes

Webb reveals evidence of three massive black holes in a galaxy from the dawn of the universe

The three active black holes were found in galaxy J0148-4214 as it appeared about 1.2 billion years after the Big Bang. The finding strengthens the possibility that mergers accelerated the growth of black holes in the early universe.
Mapping of about half a million brain cells: In depression, the creation of new neurons stalls before maturation

Mapping of about half a million brain cells: In depression, the creation of new neurons stalls before maturation

Researchers at Columbia University have identified more dormant stem cells and fewer young, maturing neurons in the brains of adults with major depression. The study, published in Nature Medicine, also points to widespread disruptions in brain circuits.