December 4st, 2025

Human cells that have undergone gene editing using a novel retron-based gene editing technology. The orange dots indicate successful gene edits. The green dots show a fluorescent protein tag on the surface of mitochondria. Credit: Yu-Cheon Chang / The University of Texas at Austin.

New retron-based DNA editing method to replace CRISPR offers hope for broad treatment of complex genetic diseases

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Researchers at the University of Texas at Austin have developed a gene editing technique that can replace damaged DNA segments in their entirety, simultaneously correct a variety of rare mutations, and achieve an efficiency of about 30% of target cells – with initial applications
The binary system, one of whose members is the black hole Cygnus X-1. From Wikipedia

Balloon-launched telescope observations reveal how material falls into the black hole in Cygnus X-1

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A team of researchers used the balloon-borne XL-Calibur telescope to measure polarized X-rays from the black hole Cygnus X-1 in unprecedented detail, revealing new clues about how hot material twists and turns.
The relationship between the various formulas of pi. Illustration: Ramanujan's group led by Prof. Ido Kaminer from the Viterbi Faculty of Electrical and Computer Engineering at the Technion.

The "Ramanujan Machine" group from the Technion reveals deep connections between hundreds of formulas and the constant π

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