October 29, 2012

Embryonic stem cells that develop into gametes, from which the gene encoding the Utx enzyme has been deleted, are labeled with a bright green fluorescent protein. In each of the columns is marked (in red, purple or orange) a gene essential for the survival and development of the gametes. A comparison of the tenth day of cell development (top row) with day 12 (bottom row) shows that the expression of the four essential genes is stopped. As a result, the stem cells do not develop into sperm or egg cells, but die. Photo: Weizmann Institute

back to the Future

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Figure 3: What is meant by genetic mutation, and what is the chance of a sick offspring?

So what do you do there at the university? Chapter 10: On developing a research model for 'orphan' diseases

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