Researchers claim to have found molecules that may allow carriers not to develop the disease
Tamara Traubman
16 years ago, in the early years of the AIDS epidemic, a virus expert named Dr. Jay Levy from the University of California, San Francisco, found evidence that researchers had difficulty understanding. Levy discovered that the cells of the immune system secrete a substance that can stop the AIDS virus - HIV. It is possible. , Levy suggested, that if this substance is found in high levels in the bodies of humans infected with the virus, they will still be able to continue living for a long time without developing the disease.
Several research groups began to search for the substance, the identity of which has so far remained unknown - despite many efforts and six substances that were proposed over the years as candidates and later rejected.
In a research report, which will be published today (Friday) in the scientific journal "Science", researchers from an American team claim that they have found the substance. According to them, these are three small molecules, which were already known, and are called alpha-definisin-2, 1 and 3 The researchers, Dr. David Hu and Dr. Linky Zhang of the Aaron Diamond Center for AIDS Research in New York, say that in laboratory cell cultures, the molecules inhibited the AIDS virus culture. According to them, the cold molecules may point to new directions for the development of new AIDS drugs.
Some scientists said they found the data Shu and Zhang presented compelling. But other researchers have expressed doubts about the possibility that this is the material Levy was talking about. In the study, they said, very few people were tested; Some of the properties that Levy was able to discover in his material do not exist in this material and it is not at all clear at the moment through which mechanism alpha-definisin can inhibit the spread of the virus.
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